Microstructure, mechanical and corrosion properties and biocompatibility of Mg-Zn-Mn alloys for biomedical application

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	Microstructure, mechanical and corrosion properties and biocompatibility of Mg-Zn-Mn alloys for biomedical application
	E. L. Zhang; D. S. Yin; L. P. Xu; L. Yang; K. Yang
	2009
发表期刊	Materials Science & Engineering C-Biomimetic and Supramolecular Systems
ISSN	0928-4931
卷号	29 期号:3 页码:987-993
摘要	Mn and Zn were selected to develop a Mg-Zn-Mn magnesium alloy for biomedical application due to the good biocompatibility of Zn and Mn elements. Microstructure, mechanical properties, corrosion properties and biocompatibility of the Mg-Zn-Mn alloys have been investigated by use of optical microscope, scanning electron microscope, tensile testing, and blood hemolysis and cell toxicity. Microstructure observation has shown that the addition of Zn and the extrusion significantly refined the grain size of both the as-cast and the extruded magnesium alloys, which mainly contributes to the high tensile strength and good elongation. Polarization test has shown Zn could accelerate the formation of a passivation film, which provides good protection to the magnesium alloy against simulate body fluid. Cell culture and hemolysis tests have shown that the magnesium alloy did not have cell toxicity, showing good cytocompatibility, but the alloy caused hemolysis to blood system. It was suggested that surface modification have to be adopted to improve the blood compatibility of the magnesium alloy for the application in blood environment. (C) 2008 Elsevier B.V. All rights reserved.
部门归属	[zhang, erlin; xu, liping; yang, lei; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. [yin, dongsong] harbin inst technol, sch mat sci & engn, harbin 150001, peoples r china.;zhang, el (reprint author), chinese acad sci, inst met res, shenyang 110016, peoples r china;erlin.zhang@imr.ac.cn
关键词	Magnesium Biomaterials Mechanical Property Corrosion Biocompatibility Cell Toxicity In-vivo Corrosion Magnesium Alloy Phosphate Coatings Hanks Solution Behavior Bone Surface Growth
URL	查看原文
WOS记录号	WOS:000266520400058
引用统计	被引频次：393[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/32529
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	E. L. Zhang,D. S. Yin,L. P. Xu,et al. Microstructure, mechanical and corrosion properties and biocompatibility of Mg-Zn-Mn alloys for biomedical application[J]. Materials Science & Engineering C-Biomimetic and Supramolecular Systems,2009,29(3):987-993.
APA	E. L. Zhang,D. S. Yin,L. P. Xu,L. Yang,&K. Yang.(2009).Microstructure, mechanical and corrosion properties and biocompatibility of Mg-Zn-Mn alloys for biomedical application.Materials Science & Engineering C-Biomimetic and Supramolecular Systems,29(3),987-993.
MLA	E. L. Zhang,et al."Microstructure, mechanical and corrosion properties and biocompatibility of Mg-Zn-Mn alloys for biomedical application".Materials Science & Engineering C-Biomimetic and Supramolecular Systems 29.3(2009):987-993.