A new strategy for assembling multifunctional nanocomposites with iron oxide and amino-terminated PAMAM dendrimers

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	A new strategy for assembling multifunctional nanocomposites with iron oxide and amino-terminated PAMAM dendrimers
	Y. Zhang; J. Y. Liu; F. Yang; Y. J. Zhang; Q. Yao; T. Y. Cui; X. Zhao; Z. D. Zhang
	2009
发表期刊	Journal of Materials Science-Materials in Medicine
ISSN	0957-4530
卷号	20 期号:12 页码:2433-2440
摘要	A new strategy for assembling multifunctional nanocomposites with magnetic particles and amino dendrimers was reported. In this strategy, the amino terminated PAMAM G5.0 and Fe(3)O(4) NPs prepared by co-deposition method and further modified by aminosilane by two sol-gel processes were combined with the hydrophilic spacer of PEG dicarboxylate by amidation. The nanocomposites were characterized by means of X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), atom force microscopy (AFM), superconducting quantum interference device (SQUID) magnetometer, and hydrophilicity analysis. The results showed that the multifunctional nanocomposites were spherical with the mean diameter of 180 nm and exhibited good dispersion and hydrophilicity. The new strategy put forward here provides an effective route to functionalizing Fe(3)O(4) NPs with various amino dendrimers for drug and gene delivery as well as biological detection.
部门归属	[zhang, ying; yang, fang; zhang, ya-jing; yao, qi; cui, tie-yu; zhang, zhi-dong] chinese acad sci, shenyang natl lab mat sci, inst met res, shenyang 110016, peoples r china. [zhang, ying; yang, fang; zhang, ya-jing; yao, qi; cui, tie-yu; zhang, zhi-dong] chinese acad sci, int ctr mat phys, shenyang 110016, peoples r china. [zhang, ying; liu, jing-ying; zhao, xiang] shen yang pharmaceut univ, coll pharmaceut engn, shenyang 110016, peoples r china.;zhang, y (reprint author), chinese acad sci, shenyang natl lab mat sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china;yzhang7704@imr.ac.cn
关键词	Magnetic Nanoparticles Gold Nanoparticles Cancer-cells Delivery Drug Vesicles Systems Carrier Spheres Fusion
URL	查看原文
WOS记录号	WOS:000272616800009
引用统计	被引频次：17[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/32580
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	Y. Zhang,J. Y. Liu,F. Yang,et al. A new strategy for assembling multifunctional nanocomposites with iron oxide and amino-terminated PAMAM dendrimers[J]. Journal of Materials Science-Materials in Medicine,2009,20(12):2433-2440.
APA	Y. Zhang.,J. Y. Liu.,F. Yang.,Y. J. Zhang.,Q. Yao.,...&Z. D. Zhang.(2009).A new strategy for assembling multifunctional nanocomposites with iron oxide and amino-terminated PAMAM dendrimers.Journal of Materials Science-Materials in Medicine,20(12),2433-2440.
MLA	Y. Zhang,et al."A new strategy for assembling multifunctional nanocomposites with iron oxide and amino-terminated PAMAM dendrimers".Journal of Materials Science-Materials in Medicine 20.12(2009):2433-2440.