Antibacterial mechanism of copper-bearing antibacterial stainless steel against E.coli

IMR OpenIR

	Antibacterial mechanism of copper-bearing antibacterial stainless steel against E.coli; Antibacterial mechanism of copper-bearing antibacterial stainless steel against E.coli
	L. Nan; W. C. Yang; Y. Q. Liu; H. Xu; Y. Li; M. Q. Lu; K. Yang
	2008 ; 2008
发表期刊	Journal of Materials Science & Technology ; Journal of Materials Science & Technology
ISSN	1005-0302 ; 1005-0302
卷号	24 期号:2 页码:197-201
摘要	A preliminary study was made on the antibacterial mechanism of copper-bearing antibacterial stainless steels against E.coli through experiments of microbiology such as EDTA (ethylenediaminetetraacetic acid) complexing, DNA smearing and AFM (atomic force microscope) observation. It was measured that the antibacterial stainless steels showed excellent antibacterial functions with antibacterial rate to E.coli over 99.99%. The antibacterial rate was weak if the bacteria solution was complexed by EDTA, indicating that the copper ions play a dominant role in the antibacterial effect of the antibacterial stainless steels. The electrophoresis experiment did not show the phenomenon of DNA smearing for E.coli after contacting antibacterial stainless steels, which meant that DNA of E.coli was not obviously damaged. It was observed by AFM that the morphology of E.coli changed a lot after contacting antibacterial stainless steels, such as cell walls being seriously changed and lots of contents in the cells being leaked.; A preliminary study was made on the antibacterial mechanism of copper-bearing antibacterial stainless steels against E.coli through experiments of microbiology such as EDTA (ethylenediaminetetraacetic acid) complexing, DNA smearing and AFM (atomic force microscope) observation. It was measured that the antibacterial stainless steels showed excellent antibacterial functions with antibacterial rate to E.coli over 99.99%. The antibacterial rate was weak if the bacteria solution was complexed by EDTA, indicating that the copper ions play a dominant role in the antibacterial effect of the antibacterial stainless steels. The electrophoresis experiment did not show the phenomenon of DNA smearing for E.coli after contacting antibacterial stainless steels, which meant that DNA of E.coli was not obviously damaged. It was observed by AFM that the morphology of E.coli changed a lot after contacting antibacterial stainless steels, such as cell walls being seriously changed and lots of contents in the cells being leaked.
部门归属	[nan, li; liu, yongqian; li, ying; lu, manqi; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. [yang, weichao; xu, hui] chinese acad sci, inst appl ecol, shenyang 110016, peoples r china. [nan, li; yang, weichao; liu, yongqian] chinese acad sci, grad sch, beijing 100049, peoples r china.;yang, k (reprint author), chinese acad sci, inst met res, shenyang 110016, peoples r china;kyang@imr.ac.cn ; [nan, li; liu, yongqian; li, ying; lu, manqi; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. [yang, weichao; xu, hui] chinese acad sci, inst appl ecol, shenyang 110016, peoples r china. [nan, li; yang, weichao; liu, yongqian] chinese acad sci, grad sch, beijing 100049, peoples r china.;yang, k (reprint author), chinese acad sci, inst met res, shenyang 110016, peoples r china;kyang@imr.ac.cn
关键词	Copper Copper Stainless Steel Stainless Steel E.coli E.coli Antibacterial Mechanism Antibacterial Mechanism Implantation Implantation
URL	查看原文 ; 查看原文
WOS记录号	WOS:000254637200012 ; WOS:000254637200012
引用统计	被引频次：57[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/33038
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	L. Nan,W. C. Yang,Y. Q. Liu,et al. Antibacterial mechanism of copper-bearing antibacterial stainless steel against E.coli, Antibacterial mechanism of copper-bearing antibacterial stainless steel against E.coli[J]. Journal of Materials Science & Technology, Journal of Materials Science & Technology,2008, 2008,24, 24(2):197-201, 197-201.
APA	L. Nan.,W. C. Yang.,Y. Q. Liu.,H. Xu.,Y. Li.,...&K. Yang.(2008).Antibacterial mechanism of copper-bearing antibacterial stainless steel against E.coli.Journal of Materials Science & Technology,24(2),197-201.
MLA	L. Nan,et al."Antibacterial mechanism of copper-bearing antibacterial stainless steel against E.coli".Journal of Materials Science & Technology 24.2(2008):197-201.