One-step synthesis of biocompatible gold nanoparticles using gallic acid in the presence of poly-(N-vinyl-2-pyrrolidone)

IMR OpenIR

	One-step synthesis of biocompatible gold nanoparticles using gallic acid in the presence of poly-(N-vinyl-2-pyrrolidone)
	W. X. Wang; Q. F. Chen; C. Jiang; D. Z. Yang; X. M. Liu; S. K. Xu
	2007
发表期刊	Colloids and Surfaces a-Physicochemical and Engineering Aspects
ISSN	0927-7757
卷号	301 期号:1-3 页码:73-79
摘要	A one-step method for the synthesis of biocompatible gold nanoparticles at room temperature by reducing HAUCl(4) with gallic acid in the presence of poly-(N-vinyl-2-pyrrolidone) (PVP) is presented. The effect of the molar ratio of gallic acid to gold (R) on the size and shape of gold nanoparticles and the characteristic of gold nanoparticles was investigated by UV-vis and infrared spectroscopy, transmission electron microscopy, and X-ray diffraction. For an R value of about 0.4, the prepared gold nanoparticles were the smallest in size and the most close to spherical in shape. At other molar ratios, particle sizes increased and various polyhedra were formed. A reaction mechanism for the reduction of HAuCl(4) by gallic acid is proposed. The incorporation of PVP effectively protected the surface of gold nanoparticles and improved their stability. The PVP-protected gold nanoparticles were modified with 3'- and 5'-alkanethiol-capped 12-base oligonucleotides, respectively, to form two different nucleic acid probes. The probes were successfully used to complex a 24-base complementary polynucleotide target in a tail-to-tail fashion. (C) 2006 Elsevier B.V. All rights reserved.
部门归属	northeastern univ, dept chem, shenyang 110004, liaoning, peoples r china. chinese acad sci, shenyang natl lab mat sci, inst met res, shenyang 110016, liaoning, peoples r china.;xu, sk (reprint author), northeastern univ, dept chem, shenyang 110004, liaoning, peoples r china;xushukun46@126.com
关键词	Gold Nanoparticles Synthesis Gallic Acid Poly-(N-vinyl-2-pyrrolidone) (Pvp) Dna Hybridization Size-controlled Synthesis Optical-properties Colloidal Gold Shape Control Irradiation Particles Polymers Thiols Nucleation Reduction
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WOS记录号	WOS:000246835400011
引用统计	被引频次：138[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/33875
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	W. X. Wang,Q. F. Chen,C. Jiang,et al. One-step synthesis of biocompatible gold nanoparticles using gallic acid in the presence of poly-(N-vinyl-2-pyrrolidone)[J]. Colloids and Surfaces a-Physicochemical and Engineering Aspects,2007,301(1-3):73-79.
APA	W. X. Wang,Q. F. Chen,C. Jiang,D. Z. Yang,X. M. Liu,&S. K. Xu.(2007).One-step synthesis of biocompatible gold nanoparticles using gallic acid in the presence of poly-(N-vinyl-2-pyrrolidone).Colloids and Surfaces a-Physicochemical and Engineering Aspects,301(1-3),73-79.
MLA	W. X. Wang,et al."One-step synthesis of biocompatible gold nanoparticles using gallic acid in the presence of poly-(N-vinyl-2-pyrrolidone)".Colloids and Surfaces a-Physicochemical and Engineering Aspects 301.1-3(2007):73-79.