Calcium phosphate coating of Ti-Nb-Zr-Sn titanium alloy

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	Calcium phosphate coating of Ti-Nb-Zr-Sn titanium alloy
	C. Y. Zheng; S. J. Li; X. J. Tao; Y. L. Hao; R. Yang; L. Zhang
	2007
发表期刊	Materials Science & Engineering C-Biomimetic and Supramolecular Systems
ISSN	0928-4931
卷号	27 期号:4 页码:824-831
摘要	This study focuses on rapid formation of calcium phosphate coating on a beta type Ti-Nb-Zr-Sn biomedical titanium alloy by alkali treatment. The results show that a bioconductive surface layer forms on specimens immersed in 1-5 M KOH solution but only treatment in 1 M KOH avoids formation of crevices, producing a potassium titanate layer with porous network structure. Heat treatment at 600 degrees C after the alkali treatment promotes titanate growth. Following the above treatments, a continuous apatite layer forms within 4 h of soaking in a calcium phosphate solution with high ionic concentration. Such rapid apatite formation is due to high concentration of calcium ions in the solution used in this study and the buffering function of NaHCO3. Results of dissolution experiment show that Ca and P ions release gradually from the coating during soaking in a 0.9% NaCl solution, which may be helpful to the formation of natural bone if implanted in human body. Cell culture experiment shows that the apatite layer favours adhesion and proliferation of rat osteoblast as compared with coating-free Ti-Nb-Zr-Sn alloy and commercially pure titanium (CP Ti). (C) 2006 Elsevier B.V. All rights reserved.
部门归属	chinese acad sci, met res inst, shenyang natl lab mat sci, shenyang 110016, peoples r china. china med univ, affiliated hosp 2, dept stomatol, shenyang 110004, peoples r china.;yang, r (reprint author), chinese acad sci, met res inst, shenyang natl lab mat sci, 72 wenhua rd, shenyang 110016, peoples r china;ryang@imr.ac.cn
关键词	Biomedical Titanium Alloys Surface Treatment Calcium Phosphate Coating Dissolution Osteoblast Adhesion And Proliferation Chemically Treated Titanium Simulated Body-fluid Apatite Formation Constant Undersaturation Hydroxyapatite Coatings Biomedical Applications Dissolution Behavior Surface Modification Biomimetic Method Low-temperature
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WOS记录号	WOS:000246630600036
引用统计	被引频次：47[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/34081
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	C. Y. Zheng,S. J. Li,X. J. Tao,et al. Calcium phosphate coating of Ti-Nb-Zr-Sn titanium alloy[J]. Materials Science & Engineering C-Biomimetic and Supramolecular Systems,2007,27(4):824-831.
APA	C. Y. Zheng,S. J. Li,X. J. Tao,Y. L. Hao,R. Yang,&L. Zhang.(2007).Calcium phosphate coating of Ti-Nb-Zr-Sn titanium alloy.Materials Science & Engineering C-Biomimetic and Supramolecular Systems,27(4),824-831.
MLA	C. Y. Zheng,et al."Calcium phosphate coating of Ti-Nb-Zr-Sn titanium alloy".Materials Science & Engineering C-Biomimetic and Supramolecular Systems 27.4(2007):824-831.