Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions

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	Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions
	T. Hou; J. Z. Zhang; L. J. Kong; X. F. Zhang; P. Hu; D. M. Zhang; N. Li
	2006
发表期刊	Journal of Biomaterials Science-Polymer Edition
ISSN	0920-5063
卷号	17 期号:7 页码:735-746
摘要	Polyhydroxybutyrate (PHB) films were implanted with 40 keV hydroxyl ions with fluences ranging from 1 X 10(12) to 1 X 10(15) ions/cm2, respectively. The as-implanted PHB films were characterized by scanning electron microscopy (SEM), electron spectroscopy for chemical analysis (ESCA) and water contact angle measurements. The surface structures and properties of the as-implanted PHB films were closely related with hydroxyl ion fluence. They were further investigated by inoculating 3T6 fibroblasts cells on their surfaces. Morphologies of the 3T6 fibroblast cells cultured on surfaces of the as-implanted PHB films were observed by SEM. Characterization of the cultural 3T6 cells was analyzed qualitatively. The preliminary experimental results reveal that the bioactivity of the PHB films modified by hydroxyl ion implantation was improved at different levels, and the fluence of 1 X 10(13) ionS/cm(2) is optimal for PHB film.
部门归属	tsing hua univ, dept mat sci & engn, adv mat lab, beijing 100084, peoples r china. chinese acad sci, int ctr mat phys, shenyang 110016, peoples r china. tsing hua univ, dept biol sci & biotechnol, beijing 100084, peoples r china. tsing hua univ, dept chem engn, beijing 100084, peoples r china.;zhang, jz (reprint author), tsing hua univ, dept mat sci & engn, adv mat lab, beijing 100084, peoples r china;zjz@mail.tsinghua.edu.cn
关键词	Tissue Engineering Ion implantatIon Cell Culture Bioactivity Cross-linking 3-dimensional Scaffolds Tissue Regeneration Dermal Substitute Collagen Polyhydroxyalkanoates Gelatin Reconstruction Polyethylene Replacement
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WOS记录号	WOS:000239480000002
引用统计	被引频次：5[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/34243
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	T. Hou,J. Z. Zhang,L. J. Kong,et al. Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions[J]. Journal of Biomaterials Science-Polymer Edition,2006,17(7):735-746.
APA	T. Hou.,J. Z. Zhang.,L. J. Kong.,X. F. Zhang.,P. Hu.,...&N. Li.(2006).Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions.Journal of Biomaterials Science-Polymer Edition,17(7),735-746.
MLA	T. Hou,et al."Morphologies of fibroblast cells cultured on surfaces of PHB films implanted by hydroxyl ions".Journal of Biomaterials Science-Polymer Edition 17.7(2006):735-746.