High nitrogen nickel-free austenitic stainless steel: A promising coronary stent material

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	High nitrogen nickel-free austenitic stainless steel: A promising coronary stent material
	K. Yang; Y. B. Ren; P. Wan
	2012
发表期刊	Science China-Technological Sciences
ISSN	1674-7321
卷号	55 期号:2 页码:329-340
摘要	Currently commercialized coronary stents are mainly made of the medical 316L stainless steel and cobalt-based alloy (L605) due to their good combination of properties, especially excellent mechanical properties. However, the presence of high quantity of nickel and/or cobalt elements, the agents known to trigger the toxic and allergic responses, in these materials has caused many clinic concerns. The potential adverse effect of nickel ions release has prompted the development of high nitrogen nickelfree austenitic stainless steels for medical application. Nitrogen in steel is not only to replace the nickel but also improve the properties of steel. In this paper, the harmfulness and release of nickel from metallic stents, and the advantages in mechanical properties and hemocompatibility of high nitrogen nickel-free stainless steels for coronary stents are reviewed. Apart from the highlight of nickel-free, the superiority of high strength and better hemocompatibility of high nitrogen nickel-free stainless steels can guarantee to manufacture thinner strut coronary stents with remarkable anticoagulation ability. High nitrogen nickelfree stainless steels as a promising coronary stents material will attract more and more clinical doctors and stents makers to bring them into clinical application.
部门归属	[yang ke; ren yibin; wan peng] chinese acad sci, inst met res, shenyang 110016, peoples r china.;yang, k (reprint author), chinese acad sci, inst met res, shenyang 110016, peoples r china.;kyang@imr.ac.cn
关键词	High Nitrogen Steel Nickel-free Biocompatibility Coronary Stent Restenosis Drug-eluting Stents Metal-ion Release In-vivo Corrosion Medical Applications Endothelial-cells Strut Thickness Human-body Vitro Restenosis Behavior
URL	查看原文
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/60393
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	K. Yang,Y. B. Ren,P. Wan. High nitrogen nickel-free austenitic stainless steel: A promising coronary stent material[J]. Science China-Technological Sciences,2012,55(2):329-340.
APA	K. Yang,Y. B. Ren,&P. Wan.(2012).High nitrogen nickel-free austenitic stainless steel: A promising coronary stent material.Science China-Technological Sciences,55(2),329-340.
MLA	K. Yang,et al."High nitrogen nickel-free austenitic stainless steel: A promising coronary stent material".Science China-Technological Sciences 55.2(2012):329-340.