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Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats
Y. Guo; L. Ren; C. Liu; Y. J. Yuan; X. Lin; L. L. Tan; S. R. Chen; K. Yang; X. F. Mei
2013
Source PublicationMaterials Science & Engineering C-Materials for Biological Applications
ISSN0928-4931
Volume33Issue:7Pages:4470-4474
AbstractThe study was focused on the implantation of a biodegradable AZ31 magnesium alloy into the femoral periosteal of the osteoporosis modeled rats. The experimental results showed that after 4 weeks implantation of AZ31 alloy in the osteoporosis modeled rats, the expression of BMP-2 in bone tissues of the rats was much enhanced, even higher than the control group, which should promote the bone formation and be beneficial for reducing the harmful effect of osteoporosis. Results of HE stains showed that the implantation of AZ31 alloy did not have obvious pathological changes on both the liver and kidney of the animal. (C) 2013 Elsevier B.V. All rights reserved.
description.department[guo, yue ; liu, chang ; yuan, yajiang ; chen, shurui ; mei, xifan] liaoning med univ, jinzhou 121000, peoples r china. [ren, ling ; lin, xiao ; tan, lili ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. ; yang, k (reprint author), chinese acad sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china. ; 373073766@qq.com ; lren@imr.ac.cn ; meixifan1971@163.com ; yuan925@163.com ; linx@imr.ac.cn ; lltan@imr.ac.cn ; 272146792@qq.com ; kyang@imr.ac.cn ; meixifan1971@163.com
KeywordMagnesium Alloy Bmp-2 Osteoporosis Osteoblast Differentiation
URL查看原文
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/71240
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
Y. Guo,L. Ren,C. Liu,et al. Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats[J]. Materials Science & Engineering C-Materials for Biological Applications,2013,33(7):4470-4474.
APA Y. Guo.,L. Ren.,C. Liu.,Y. J. Yuan.,X. Lin.,...&X. F. Mei.(2013).Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats.Materials Science & Engineering C-Materials for Biological Applications,33(7),4470-4474.
MLA Y. Guo,et al."Effect of implantation of biodegradable magnesium alloy on BMP-2 expression in bone of ovariectomized osteoporosis rats".Materials Science & Engineering C-Materials for Biological Applications 33.7(2013):4470-4474.
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