IMR OpenIR
Effect of nanotube diameters on bioactivity of a multifunctional titanium alloy
Y. Q. Hao; S. J. Li; Y. L. Hao; Y. K. Zhao; H. J. Ai
2013
Source PublicationApplied Surface Science
ISSN0169-4332
Volume268Pages:44-51
AbstractTi-24Nb-4Zr-8Sn (abbreviated as Ti2448) is a multifunctional beta type titanium alloy consisting of nontoxic alloying elements and possessing better balanced biomechanical properties of high strength and low elastic modulus. To improve its bioactivity, the anodic oxidation of Ti2448 alloy in neutral electrolyte containing small amounts of NH4F was applied to produce the nanotubes consisting of the amorphous mixed oxides of TiO2, Nb2O5, SnO2 and ZrO2. The in vitro studies of the oestoblast-like MG-63 cells were performed to evaluate the biological behavior of the nanotubes with the outer diameters of 30, 50, 70 and 90 nm in comparison with the polished pure titanium and Ti2448 alloy. The results showed that the smaller diameter of 30 nm promoted the cell adhesion, proliferation and differentiation whereas the larger diameter of 90 nm had the worst cell viability with small spreading area of cytoskeletal actin. Although the nanotubes of Ti2448 alloy consist of the amorphous mixed oxides, it exhibits similar biological behavior with that of the amorphous TiO2 of pure titanium. This suggests that the topography of the amorphous nanotube plays important role on cell response. Additionally, the studies did not detect statistical difference of the bioactivity for the polished pure titanium and Ti2448 alloy. (C) 2012 Elsevier B. V. All rights reserved.
description.department[hao, y. q. ; ai, h. j.] china med univ, sch stomatol, dept prosthodont, shenyang 110002, peoples r china. [li, s. j. ; hao, y. l.] chinese acad sci, inst met res, shenyang natl lab mat sci, shenyang 110016, peoples r china. [zhao, y. k.] china med univ, r&d ctr biotechnol, shenyang 110163, peoples r china. ; ai, hj (reprint author), china med univ, sch stomatol, dept prosthodont, 117 nanjingbei st, shenyang 110002, peoples r china. ; aih0620@yahoo.com.cn
KeywordAnodic Oxidation Nanotube Bioactivity Multifunctional Titanium Alloy Cell Response Surface Biocompatibility Implants Modulus Stress Ti-13nb-13zr Wettability Osteoblasts Coatings
URL查看原文
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/71251
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
Y. Q. Hao,S. J. Li,Y. L. Hao,et al. Effect of nanotube diameters on bioactivity of a multifunctional titanium alloy[J]. Applied Surface Science,2013,268:44-51.
APA Y. Q. Hao,S. J. Li,Y. L. Hao,Y. K. Zhao,&H. J. Ai.(2013).Effect of nanotube diameters on bioactivity of a multifunctional titanium alloy.Applied Surface Science,268,44-51.
MLA Y. Q. Hao,et al."Effect of nanotube diameters on bioactivity of a multifunctional titanium alloy".Applied Surface Science 268(2013):44-51.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Y. Q. Hao]'s Articles
[S. J. Li]'s Articles
[Y. L. Hao]'s Articles
Baidu academic
Similar articles in Baidu academic
[Y. Q. Hao]'s Articles
[S. J. Li]'s Articles
[Y. L. Hao]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Y. Q. Hao]'s Articles
[S. J. Li]'s Articles
[Y. L. Hao]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.