The in vitro degradation process and biocompatibility of a ZK60 magnesium alloy with a forsterite-containing micro-arc oxidation coating

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	The in vitro degradation process and biocompatibility of a ZK60 magnesium alloy with a forsterite-containing micro-arc oxidation coating
	X. Lin; L. L. Tan; Q. Zhang; K. Yang; Z. Q. Hu; J. H. Qiu; Y. Cai
	2013
发表期刊	Acta Biomaterialia
ISSN	1742-7061
卷号	9 期号:10 页码:8631-8642
摘要	Magnesium has attracted much attention as a class of biodegradable metallic biomaterials. In this study, a silicate electrolyte-based micro-arc oxidation (MAO) treatment was adopted to prepare forsterite-containing MAO coatings on a ZK60 magnesium alloy in order to decrease the degradation rate and increase the biological property of the alloy. Four anodization voltages were chosen to prepare the MAO coatings. The cell experiment showed a cytotoxicity of grade 0 for the MAO-coated alloy to L929 cells and the hemolytic ratio was dramatically decreased for the MAO-coated alloy compared with the bare one. The corrosion resistance and the degradation behavior of the MAO-coated ZK60 alloy were studied using drop tests, electrochemical measurements and immersion tests. The results indicate that the MAO coating could effectively decrease the initial degradation rate of the alloy. The corrosion resistance of MAO coating was increased with the elevation of the preparation voltage. A degradation model for ZK60 alloy with a forsterite-containing MAO coating was proposed. Based on the model, the MAO-coated alloy experiences destruction and restoration simultaneously, and the coating fails in a peeling-off mode. (C) 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
部门归属	[lin, xiao ; tan, lili ; yang, ke ; hu, zhuangqi] chinese acad sci, inst met res, shenyang 110016, peoples r china. [zhang, qiang] chinese peoples liberat army gen hosp, dept orthopaed, beijing 100853, peoples r china. [qiu, jianhong ; cai, yong] trauson med instrument co ltd, changzhou 213163, peoples r china. ; yang, k (reprint author), chinese acad sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china. ; kyang@imr.ac.cn
关键词	Biodegradable Magnesium Zk60 Microarc Oxidation Degradation In Vitro Plasma Electrolytic Oxidation Electrochemical Corrosion Behavior Vivo Corrosion Zn Alloy Bone Microstructure Silicate Bioceramics Zirconium Zinc
URL	查看原文
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/71351
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	X. Lin,L. L. Tan,Q. Zhang,et al. The in vitro degradation process and biocompatibility of a ZK60 magnesium alloy with a forsterite-containing micro-arc oxidation coating[J]. Acta Biomaterialia,2013,9(10):8631-8642.
APA	X. Lin.,L. L. Tan.,Q. Zhang.,K. Yang.,Z. Q. Hu.,...&Y. Cai.(2013).The in vitro degradation process and biocompatibility of a ZK60 magnesium alloy with a forsterite-containing micro-arc oxidation coating.Acta Biomaterialia,9(10),8631-8642.
MLA	X. Lin,et al."The in vitro degradation process and biocompatibility of a ZK60 magnesium alloy with a forsterite-containing micro-arc oxidation coating".Acta Biomaterialia 9.10(2013):8631-8642.