A new antibacterial titanium-copper sintered alloy: Preparation and antibacterial property

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	A new antibacterial titanium-copper sintered alloy: Preparation and antibacterial property
	E. L. Zhang; F. B. Li; H. Y. Wang; J. Liu; C. M. Wang; M. Q. Li; K. Yang
	2013
发表期刊	Materials Science & Engineering C-Materials for Biological Applications
ISSN	0928-4931
卷号	33 期号:7 页码:4280-4287
摘要	Copper element was added in pure titanium by a powder metallurgy to produce a new antibacterial titanium-copper alloy (Ti-Cu alloy). This paper reported the very early stage results, emphasizing on the preparation, mechanical property and antibacterial activity. The phase constitution was analyzed by XRD and the microstructure was observed under SEM equipped with EDS. The hardness, the compressive strength and the corrosion resistance of Ti-Cu alloy were tested in comparison with cp-Ti. The antibacterial property of the Ti-Cu alloy was assessed by two methods: agar diffusion assay and plate-count method, in which Staphylococcus aureus (S. aureus) and Escherichia coil (E. coil) were used. XRD and SEM results showed that Ti2Cu phase and Cu-rich phase were synthesized in the Ti-Cu sintered alloy, which significantly increases the hardness and the compressive strength compared with cp-Ti and slightly improves the corrosion resistance. No antibacterial activity was detected by the agar diffusion assay on the Ti-Cu alloy, but the plate-count results indicated that the Ti-Cu alloy exhibited strong antibacterial property against both bacteria even after three polishing treatments, which demonstrates strongly that the whole alloy is of antibacterial activity. The antibacterial mechanism was thought to be in associated with the Cu ion released from the Ti-Cu alloy. (C) 2013 Elsevier B.V. All rights reserved.
部门归属	[zhang, erlin ; li, fangbing ; wang, hongying ; liu, jie ; wang, chunmin ; li, muqin] jiamusi univ, jiamusi 154007, peoples r china. [zhang, erlin] northeastern univ, sch met & mat, shenyang 110819, peoples r china. [yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. ; zhang, el (reprint author), jiamusi univ, jiamusi 154007, peoples r china. ; zhangerlin2009@163.com
关键词	Titanium Alloy Antibacterial Activity Copper Corrosion Resistance Ti-cu Alloy Mechanical Property In-vitro Bacterial Adhesion Ion-implantation Staphylococcus-epidermidis Osteoblast Functions Stainless-steel Surface Biocompatibility Biomaterials Infection
URL	查看原文
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/71675
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	E. L. Zhang,F. B. Li,H. Y. Wang,et al. A new antibacterial titanium-copper sintered alloy: Preparation and antibacterial property[J]. Materials Science & Engineering C-Materials for Biological Applications,2013,33(7):4280-4287.
APA	E. L. Zhang.,F. B. Li.,H. Y. Wang.,J. Liu.,C. M. Wang.,...&K. Yang.(2013).A new antibacterial titanium-copper sintered alloy: Preparation and antibacterial property.Materials Science & Engineering C-Materials for Biological Applications,33(7),4280-4287.
MLA	E. L. Zhang,et al."A new antibacterial titanium-copper sintered alloy: Preparation and antibacterial property".Materials Science & Engineering C-Materials for Biological Applications 33.7(2013):4280-4287.