Mg-Zn-Y alloys with long-period stacking ordered structure: In vitro assessments of biodegradation behavior

IMR OpenIR

	Mg-Zn-Y alloys with long-period stacking ordered structure: In vitro assessments of biodegradation behavior
	X. Zhao; L. L. Shi; J. Xu
	2013
发表期刊	Materials Science & Engineering C-Materials for Biological Applications
ISSN	0928-4931
卷号	33 期号:7 页码:3627-3637
摘要	Using Dulbecco's modified eagle medium (DMEM) with 10% fetal bovine serum (FBS) as simulated body fluid, degradation behavior of Mg-100 (-) (3x)(Zn1Y2)(x) (1 <= x <= 3) alloy series with long period stacking order (LPSO) structures was investigated. As indicated, with increasing the volume fraction of LPSO phase, degradation rate of the alloys is accelerated. Further refining the grain size by microalloying with zirconium and warm extrusion has a significant effect to mitigate the degradation rate of the Mg97Zn1Y2 alloy. Time-dependent behavior during degradation of the magnesium alloys can be described using an exponential decay function of W-R = exp(a + bt + ct(2)), where W-R is normalized residual mass/volume of the alloy. A parameter named as degradation half-life period (t(0.5)) is suggested to quantitatively assess the degradation rate. For the localized-corrosion controlled alloys, the t(0.5) parameter physically scales with electrochemical response Delta E which is a range between corrosion potential (E-corr) and pitting potential (E-pt). In comparison with conventional engineering magnesium alloys such as the AZ31, WE43, ZK60 and ZX60 alloys, extruded Mg-96 83Zn1Y2Zr0.17 alloy with LPSO structure exhibits a good combination of high mechanical strength, lower biodegradation rate and good biocompatibility. (C) 2013 Elsevier B.V. All rights reserved.
部门归属	[zhao, xu ; shi, ling-ling ; xu, jian] chinese acad sci, inst met res, shenyang natl lab mat sci, shenyang 110016, peoples r china. ; xu, j (reprint author), chinese acad sci, inst met res, shenyang natl lab mat sci, 72 wenhua rd, shenyang 110016, peoples r china. ; jianxu@imr.ac.cn
关键词	Degradable Implants Magnesium Alloys Long Period Stacking Order Corrosion Simulated Body Fluid Magnesium Alloys Corrosion Behavior Pure Magnesium Mechanical-properties Vivo Corrosion Degradation Microstructure Bone Susceptibility Strength
URL	查看原文
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/71715
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	X. Zhao,L. L. Shi,J. Xu. Mg-Zn-Y alloys with long-period stacking ordered structure: In vitro assessments of biodegradation behavior[J]. Materials Science & Engineering C-Materials for Biological Applications,2013,33(7):3627-3637.
APA	X. Zhao,L. L. Shi,&J. Xu.(2013).Mg-Zn-Y alloys with long-period stacking ordered structure: In vitro assessments of biodegradation behavior.Materials Science & Engineering C-Materials for Biological Applications,33(7),3627-3637.
MLA	X. Zhao,et al."Mg-Zn-Y alloys with long-period stacking ordered structure: In vitro assessments of biodegradation behavior".Materials Science & Engineering C-Materials for Biological Applications 33.7(2013):3627-3637.