Highly sensitive and selective detection of dopamine based on hollow gold nanoparticles-graphene nanocomposite modified electrode

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	Highly sensitive and selective detection of dopamine based on hollow gold nanoparticles-graphene nanocomposite modified electrode
	W. C. Zhu; T. Chen; X. M. Ma; H. Y. Ma; S. H. Chen
	2013
发表期刊	Colloids and Surfaces B-Biointerfaces
ISSN	0927-7765
卷号	111 页码:321-326
摘要	Highly dispersed hollow gold-graphene (HAu-G) nanocomposites were synthesized by a two-step method. The immobilization of hollow gold nanoparticles (HAu NPs) onto the surface of graphene sheets was achieved by mixing an aqueous solution of HAu NPs with a poly(N-vinylpyrrolidone)-functionalized graphene dispersion at room temperature. A glassy carbon electrode (GCE) was modified with the nanocomposites, and the as-prepared modified electrode displayed high electrocatalytic activity and extraordinary electronic transport properties. Amperometric detection of dopamine (DA) performed with the HAu-G modified electrode exhibits a good linearity between 0.08 and 600 mu M with a low detection limit of 0.05 mu M (S/N = 3) and also possesses good reproducibility and operational stability. The interference of ascorbic acid (AA) and uric acid (UA) can be excluded when using differential pulse voltammetric technique. In addition, this type of modified electrode can also be applied to the determination of DA content in dopamine hydrochloride injection. It is obvious that the HAu-G modified electrode provides a new way to detect dopamine sensitively and selectively. (C) 2013 Elsevier B.V. All rights reserved.
部门归属	[zhu, wencai ; chen, ting ; ma, xuemei ; ma, houyi] shandong univ, sch chem & chem engn, state educ minist, key lab colloid & interface chem, jinan 250100, peoples r china. [zhu, wencai] qilu normal univ, dept chem, jinan 250013, peoples r china. [chen, shenhao] state key lab corros & protect, shenyang 110016, peoples r china. ; ma, hy (reprint author), shandong univ, sch chem & chem engn, state educ minist, key lab colloid & interface chem, jinan 250100, peoples r china. ; hyma@sdu.edu.cn
关键词	Hollow Gold Nanoparticles Graphene Modified Electrode Electroanalysis Dopamine Amperometric Detection Glassy-carbon Electrode Ascorbic-acid Electrochemical Properties Methanol Electrooxidation Hybrid Material Composite Film Nanospheres Fabrication Hydroquinone Temperature
URL	查看原文
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/71754
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	W. C. Zhu,T. Chen,X. M. Ma,et al. Highly sensitive and selective detection of dopamine based on hollow gold nanoparticles-graphene nanocomposite modified electrode[J]. Colloids and Surfaces B-Biointerfaces,2013,111:321-326.
APA	W. C. Zhu,T. Chen,X. M. Ma,H. Y. Ma,&S. H. Chen.(2013).Highly sensitive and selective detection of dopamine based on hollow gold nanoparticles-graphene nanocomposite modified electrode.Colloids and Surfaces B-Biointerfaces,111,321-326.
MLA	W. C. Zhu,et al."Highly sensitive and selective detection of dopamine based on hollow gold nanoparticles-graphene nanocomposite modified electrode".Colloids and Surfaces B-Biointerfaces 111(2013):321-326.