Preliminary research on a novel bioactive silicon doped calcium phosphate coating on AZ31 magnesium alloy via electrodeposition

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	Preliminary research on a novel bioactive silicon doped calcium phosphate coating on AZ31 magnesium alloy via electrodeposition
	X. Qiu; P. Wan; L. L. Tan; X. M. Fan; K. Yang
	2014
发表期刊	Materials Science & Engineering C-Materials for Biological Applications
ISSN	0928-4931
卷号	36 页码:65-76
摘要	A silicon doped calcium phosphate coating was obtained successfully on AZ31 alloy substrate via pulse electrodeposition. A novel dual-layer structure was observed with a porous lamellar-like and outer block-like apatite layer. In vitro immersion tests were adopted in simulated body fluid within 28 days of immersion. Slow degradation rate obtained from weight loss was observed for the Si-doped Ca-P coating, which was also consistent with the results of electrochemical experiments showing an enhanced corrosion resistance for the coating. Further formation of an apatite-like layer on the surface after immersion proved better integrity and biomineralization performance of the coating. Biological characterization was carried out for viability, proliferation and differentiation of MG63 osteoblast-like cells. The coating showed a good cell growth and an enhanced cell proliferation. Moreover, an increased activity of osteogenic marker ALP was found. All the results demonstrated that the Si-doped calcium phosphate was perspective to be used as a coating for magnesium alloy implants to control the degradation rate and enhance the bioactivity, which would facilitate the rapidity of bone tissue repair. (C) 2013 Elsevier B.V. All rights reserved.
部门归属	[qiu, xun ; fan, xinmin] nanjing univ sci & technol, dept mat sci & engn, nanjing 210094, jiangsu, peoples r china. [qiu, xun ; wan, peng ; tan, lili ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. ; wan, p (reprint author), chinese acad sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china. ; pwan@imr.ac.cn
关键词	Az31 Magnesium Alloy Silicon Calcium Phosphate Coating Pulse Electrodeposition Bioactive Biodegradable Simulated Body-fluid In-vitro Biomedical Applications Bone Regeneration Mg Alloy Hydroxyapatite Corrosion Titanium Vivo Implants
URL	查看原文
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/72569
专题	中国科学院金属研究所
推荐引用方式 GB/T 7714	X. Qiu,P. Wan,L. L. Tan,et al. Preliminary research on a novel bioactive silicon doped calcium phosphate coating on AZ31 magnesium alloy via electrodeposition[J]. Materials Science & Engineering C-Materials for Biological Applications,2014,36:65-76.
APA	X. Qiu,P. Wan,L. L. Tan,X. M. Fan,&K. Yang.(2014).Preliminary research on a novel bioactive silicon doped calcium phosphate coating on AZ31 magnesium alloy via electrodeposition.Materials Science & Engineering C-Materials for Biological Applications,36,65-76.
MLA	X. Qiu,et al."Preliminary research on a novel bioactive silicon doped calcium phosphate coating on AZ31 magnesium alloy via electrodeposition".Materials Science & Engineering C-Materials for Biological Applications 36(2014):65-76.