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Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB
Q. Wang; S. Jin; X. Lin; Y. Zhang; L. Ren; K. Yang
2014
Source PublicationJournal of Materials Science & Technology
ISSN1005-0302
Volume30Issue:5Pages:487-492
AbstractMagnesium (Mg) based metals possess unique features of biodegradation that can be used for different purposes. In this study, two tumor cells, MG63 and KB, were cultured directly on a pure Mg with and without MAO coating to evaluate their cytotoxic effects on the tumor cells. It was found that both MG63 cells and KB cells adhered better on the surface of the coated Mg samples than those on the pure Mg samples. However, the survivals of two kinds of tumor cells were obviously inhibited on both Mg samples with and without coating, compared with that on the pure titanium. In addition, the survival of MG63 cells was more susceptive to the Mg degradation compared with the KB cells. Thus, the application of such effect should take account of that the degradation of Mg based metal may result in different cytotoxic effect on different cells.
description.department[wang, qiang ; jin, shi ; zhang, yang] china med univ, sch stomatol, shenyang 110002, peoples r china. [jin, shi ; ren, ling ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. ; wang, q (reprint author), china med univ, sch stomatol, shenyang 110002, peoples r china. ; mfqwang@163.com ; lren@imr.ac.cn
KeywordMagnesium Alloy Degradation Cytotoxic Effect Tumor Cell In-vitro Degradation Magnesium Scaffolds Coronary-arteries Alloy Stents
URL查看原文
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/72917
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
Q. Wang,S. Jin,X. Lin,et al. Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB[J]. Journal of Materials Science & Technology,2014,30(5):487-492.
APA Q. Wang,S. Jin,X. Lin,Y. Zhang,L. Ren,&K. Yang.(2014).Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB.Journal of Materials Science & Technology,30(5),487-492.
MLA Q. Wang,et al."Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB".Journal of Materials Science & Technology 30.5(2014):487-492.
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