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Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB
Q. Wang; S. Jin; X. Lin; Y. Zhang; L. Ren; K. Yang
2014
发表期刊Journal of Materials Science & Technology
ISSN1005-0302
卷号30期号:5页码:487-492
摘要Magnesium (Mg) based metals possess unique features of biodegradation that can be used for different purposes. In this study, two tumor cells, MG63 and KB, were cultured directly on a pure Mg with and without MAO coating to evaluate their cytotoxic effects on the tumor cells. It was found that both MG63 cells and KB cells adhered better on the surface of the coated Mg samples than those on the pure Mg samples. However, the survivals of two kinds of tumor cells were obviously inhibited on both Mg samples with and without coating, compared with that on the pure titanium. In addition, the survival of MG63 cells was more susceptive to the Mg degradation compared with the KB cells. Thus, the application of such effect should take account of that the degradation of Mg based metal may result in different cytotoxic effect on different cells.
部门归属[wang, qiang ; jin, shi ; zhang, yang] china med univ, sch stomatol, shenyang 110002, peoples r china. [jin, shi ; ren, ling ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china. ; wang, q (reprint author), china med univ, sch stomatol, shenyang 110002, peoples r china. ; mfqwang@163.com ; lren@imr.ac.cn
关键词Magnesium Alloy Degradation Cytotoxic Effect Tumor Cell In-vitro Degradation Magnesium Scaffolds Coronary-arteries Alloy Stents
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语种英语
文献类型期刊论文
条目标识符http://ir.imr.ac.cn/handle/321006/72917
专题中国科学院金属研究所
推荐引用方式
GB/T 7714
Q. Wang,S. Jin,X. Lin,et al. Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB[J]. Journal of Materials Science & Technology,2014,30(5):487-492.
APA Q. Wang,S. Jin,X. Lin,Y. Zhang,L. Ren,&K. Yang.(2014).Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB.Journal of Materials Science & Technology,30(5),487-492.
MLA Q. Wang,et al."Cytotoxic Effects of Biodegradation of Pure Mg and MAO-Mg on Tumor Cells of MG63 and KB".Journal of Materials Science & Technology 30.5(2014):487-492.
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