Anticorrosive effects and in vitro cytocompatibility of calcium silicate/zinc-doped hydroxyapatite composite coatings on titanium

IMR OpenIR

	Anticorrosive effects and in vitro cytocompatibility of calcium silicate/zinc-doped hydroxyapatite composite coatings on titanium
	Huang, Yong; Zhang, Honglei; Qiao, Haixia; Nian, Xiaofeng; Zhang, Xuejiao; Wang, Wendong; Zhang, Xiaoyun; Chang, Xiaotong; Han, Shuguang; Pang, Xiaofeng; 527238610@qq.com; xfpang@aliyun.com
	2015
发表期刊	APPLIED SURFACE SCIENCE
ISSN	0169-4332
卷号	357 页码:1776-1784
摘要	This work elucidated the corrosion resistance and cytocompatibility of electroplated Zn- and Si-containing bioactive calcium silicate/zinc-doped hydroxyapatite (ZnHA/CS) ceramic coatings on commercially pure titanium (CP-Ti). The formation of ZnHA/CS coating was investigated through Fourier transform infrared spectroscopy, X-ray diffraction (XRD), scanning electron microscopy, energy dispersive X-ray and inductively coupled plasma analyses. The XRD image showed that the reaction layer was mainly composed of HA and CaSiO3. The fabricated ZnHA/CS coatings presented a porous structure and appropriate thickness for possible applications in orthopaedic surgery. Potentiodynamic polarization tests showed that ZnHA/CS coatings exhibited higher corrosion resistance than CP-Ti. Dissolution tests on the coating also revealed that Si4+ and Zn2+ were leached at low levels. Moreover, MC3T3-E1 cells cultured on ZnHA/CS featured improved cell morphology, adhesion, spreading, proliferation and expression of alkaline phosphatase than those cultured on HA. The high cytocompatibility of ZnHA/CS could be mainly attributed to the combination of micro-porous surface effects and ion release (Zn2+ and Si4+). All these results indicate that ZnHA/CS composite-coated CP-Ti may be a potential material for orthopaedic applications. (C) 2015 Elsevier B.V. All rights reserved.
部门归属	[huang, yong ; qiao, haixia ; nian, xiaofeng ; zhang, xuejiao ; wang, wendong ; zhang, xiaoyun ; chang, xiaotong] hebei north univ, coll lab med, zhangjiakou 075000, peoples r china ; [huang, yong ; han, shuguang ; pang, xiaofeng] univ elect sci & technol china, inst life sci & technol, chengdu 610054, peoples r china ; [zhang, honglei] hebei univ, coll chem environm sci, baoding 071000, peoples r china ; [pang, xiaofeng] chinese acad sci, int ctr mat phys, shenyang 110015, peoples r china
关键词	Calcium Silicate Zinc Hydroxyapatite Anticorrosion Cytocompatibility
资助者	Science and Technology of Hebei Colleges [ZD2015124]; Natural Science Foundation of Hebei North University; High-level Scientific Research Foundation of Hebei North University; National Basic Research Program of China ("973" Program) [2011CB503700]
收录类别	sci
语种	英语
WOS记录号	WOS:000366219700059
引用统计	被引频次：33[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/74638
专题	中国科学院金属研究所
通讯作者	527238610@qq.com; xfpang@aliyun.com
推荐引用方式 GB/T 7714	Huang, Yong,Zhang, Honglei,Qiao, Haixia,et al. Anticorrosive effects and in vitro cytocompatibility of calcium silicate/zinc-doped hydroxyapatite composite coatings on titanium[J]. APPLIED SURFACE SCIENCE,2015,357:1776-1784.
APA	Huang, Yong.,Zhang, Honglei.,Qiao, Haixia.,Nian, Xiaofeng.,Zhang, Xuejiao.,...&xfpang@aliyun.com.(2015).Anticorrosive effects and in vitro cytocompatibility of calcium silicate/zinc-doped hydroxyapatite composite coatings on titanium.APPLIED SURFACE SCIENCE,357,1776-1784.
MLA	Huang, Yong,et al."Anticorrosive effects and in vitro cytocompatibility of calcium silicate/zinc-doped hydroxyapatite composite coatings on titanium".APPLIED SURFACE SCIENCE 357(2015):1776-1784.