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Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy
Ma, Zheng; Ren, Ling; Liu, Rui; Yang, Ke; Zhang, Yu; Liao, Zhenhua; Liu, Weiqiang; Qi, Min; Misra, R. D. K.; kyang@imr.ac.cn
2015
Source PublicationJOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN1005-0302
Volume31Issue:7Pages:723-732
AbstractA copper-bearing Ti-6Al-4V-5Cu alloy was processed and subjected to different heat treatments to explore the relationship among microstructure, antibacterial performance, and cytocompatibility. Characterization of microstructure revealed that the solution treated alloy consisted of alpha phase, alpha' phase and beta phase, while besides these phases, the aged alloy also contained the precipitations of intermetallic Ti2Cu compound. The solution treated alloy showed better antibacterial performance with increasing the solution temperature. The Cu ions released from Ti-6Al-4V-5Cu alloy could effectively inhibit the formation of bacterial biofilm on the surface of alloy, and do not induce any cytotoxicity. The optimal heat treatment for Ti-6Al-4V-5Cu alloy was solution treated at 930 degrees C, at which it could exhibit both promising antibacterial performance and no cytotoxicity. Copyright (C) 2015, The editorial office of Journal of Materials Science & Technology. Published by Elsevier Limited. All rights reserved.
description.department[ma, zheng ; ren, ling ; liu, rui ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china ; [ma, zheng ; qi, min] dalian univ technol, sch mat sci & engn, dalian 116024, peoples r china ; [zhang, yu] guangzhou mil gen hosp, dept orthoped, guangzhou 510010, guangdong, peoples r china ; [liao, zhenhua ; liu, weiqiang] qinghua univ, shenzhen res inst, inst med engn, shenzhen 518057, peoples r china ; [misra, r. d. k.] univ texas el paso, dept met & mat engn, el paso, tx 79968 usa
KeywordTi-6al-4v-5cu Heat Treatment Microstructure Antibacterial Performance Cytocompatibility
Funding OrganizationNational Basic Research Program of China [2012CB619101]; National Natural Science Foundation of China [81271957]; Basic Research Project of Shenzhen City [JCYJ20120616142847342]
Indexed Bysci
Language英语
WOS IDWOS:000356606700004
Citation statistics
Cited Times:63[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/74751
Collection中国科学院金属研究所
Corresponding Authorkyang@imr.ac.cn
Recommended Citation
GB/T 7714
Ma, Zheng,Ren, Ling,Liu, Rui,et al. Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2015,31(7):723-732.
APA Ma, Zheng.,Ren, Ling.,Liu, Rui.,Yang, Ke.,Zhang, Yu.,...&kyang@imr.ac.cn.(2015).Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,31(7),723-732.
MLA Ma, Zheng,et al."Effect of Heat Treatment on Cu Distribution, Antibacterial Performance and Cytotoxicity of Ti-6Al-4V-5Cu Alloy".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 31.7(2015):723-732.
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