Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application

IMR OpenIR

	Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application
	Han, Junjie; Wan, Peng; Sun, Yu; Liu, Zongyuan; Fan, Xinmin; Tan, Lili; Yang, Ke; pwan@imr.ac.cn; kyang@imr.ac.cn
	2016
发表期刊	JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN	1005-0302
卷号	32 期号:3 页码:233-244
摘要	Considering the compatibility between degradation and bioactivity of magnesium-based implants for bone repair, micro-arc oxidation is used to modify the magnesium alloy surface in aqueous electrolytes, allowing strontium, calcium, and phosphorus to be incorporated into the coating. The thickness, composition, morphology and phase of this Sr-Ca-P containing coating are characterized by scanning electron microscopy equipped with energy dispersive X-ray spectrometer and X-ray diffraction. The in vitro and in vivo degradation of the coating is evaluated by immersion test, electrochemical test and implantation test. Moreover, the cytocompatibility is tested with osteoblast cell according to ISO 10993. The results show that Sr, Ca and P elements are incorporated into the oxide coating, and a refined structure with tiny discharging micro-pores is observed on the surface of the coating. The Sr-Ca-P coating possesses a better corrosion resistance in vitro and retards the degradation in vivo. Such coating is expected to have significant medical applications on orthopedic implants and bone repair materials. Copyright (C) 2015, The editorial office of Journal of Materials Science & Technology. Published by Elsevier Limited. All rights reserved.
部门归属	[han, junjie ; fan, xinmin] nanjing univ sci & technol, dept mat sci & engn, nanjing 210094, jiangsu, peoples r china ; [han, junjie ; wan, peng ; liu, zongyuan ; tan, lili ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china ; [sun, yu] china med univ, shenyang 110002, peoples r china
关键词	Magnesium Alloy Strontium Ca-p Coating Degradation Micro-arc Oxidation
资助者	National High Technology Research and Development Program of China [2015AA033701]; Chinese Academy of Sciences-Croucher Founding Scheme for Joint Laboratories [CAS 14303]; Foundation of Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
收录类别	sci
语种	英语
WOS记录号	WOS:000370814900006
引用统计	被引频次：68[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/74842
专题	中国科学院金属研究所
通讯作者	pwan@imr.ac.cn; kyang@imr.ac.cn
推荐引用方式 GB/T 7714	Han, Junjie,Wan, Peng,Sun, Yu,et al. Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2016,32(3):233-244.
APA	Han, Junjie.,Wan, Peng.,Sun, Yu.,Liu, Zongyuan.,Fan, Xinmin.,...&kyang@imr.ac.cn.(2016).Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,32(3),233-244.
MLA	Han, Junjie,et al."Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 32.3(2016):233-244.