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Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application
Han, Junjie; Wan, Peng; Sun, Yu; Liu, Zongyuan; Fan, Xinmin; Tan, Lili; Yang, Ke; pwan@imr.ac.cn; kyang@imr.ac.cn
2016
Source PublicationJOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
ISSN1005-0302
Volume32Issue:3Pages:233-244
AbstractConsidering the compatibility between degradation and bioactivity of magnesium-based implants for bone repair, micro-arc oxidation is used to modify the magnesium alloy surface in aqueous electrolytes, allowing strontium, calcium, and phosphorus to be incorporated into the coating. The thickness, composition, morphology and phase of this Sr-Ca-P containing coating are characterized by scanning electron microscopy equipped with energy dispersive X-ray spectrometer and X-ray diffraction. The in vitro and in vivo degradation of the coating is evaluated by immersion test, electrochemical test and implantation test. Moreover, the cytocompatibility is tested with osteoblast cell according to ISO 10993. The results show that Sr, Ca and P elements are incorporated into the oxide coating, and a refined structure with tiny discharging micro-pores is observed on the surface of the coating. The Sr-Ca-P coating possesses a better corrosion resistance in vitro and retards the degradation in vivo. Such coating is expected to have significant medical applications on orthopedic implants and bone repair materials. Copyright (C) 2015, The editorial office of Journal of Materials Science & Technology. Published by Elsevier Limited. All rights reserved.
description.department[han, junjie ; fan, xinmin] nanjing univ sci & technol, dept mat sci & engn, nanjing 210094, jiangsu, peoples r china ; [han, junjie ; wan, peng ; liu, zongyuan ; tan, lili ; yang, ke] chinese acad sci, inst met res, shenyang 110016, peoples r china ; [sun, yu] china med univ, shenyang 110002, peoples r china
KeywordMagnesium Alloy Strontium Ca-p Coating Degradation Micro-arc Oxidation
Funding OrganizationNational High Technology Research and Development Program of China [2015AA033701]; Chinese Academy of Sciences-Croucher Founding Scheme for Joint Laboratories [CAS 14303]; Foundation of Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
Indexed Bysci
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/74842
Collection中国科学院金属研究所
Corresponding Authorpwan@imr.ac.cn; kyang@imr.ac.cn
Recommended Citation
GB/T 7714
Han, Junjie,Wan, Peng,Sun, Yu,et al. Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application[J]. JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,2016,32(3):233-244.
APA Han, Junjie.,Wan, Peng.,Sun, Yu.,Liu, Zongyuan.,Fan, Xinmin.,...&kyang@imr.ac.cn.(2016).Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application.JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,32(3),233-244.
MLA Han, Junjie,et al."Fabrication and Evaluation of a Bioactive Sr-Ca-P Contained Micro-Arc Oxidation Coating on Magnesium Strontium Alloy for Bone Repair Application".JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY 32.3(2016):233-244.
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