In vitro degradation of pure Mg in response to glucose

IMR OpenIR

	In vitro degradation of pure Mg in response to glucose
	Zeng, Rong-Chang; Li, Xiao-Ting; Li, Shuo-Qi; Zhang, Fen; Han, En-Hou; rczeng@foxmail.com
	2015
发表期刊	SCIENTIFIC REPORTS
ISSN	2045-2322
卷号	5 页码:-
摘要	Magnesium and its alloys are promising biodegradable biomaterials but are still challenging to be used in person with high levels of blood glucose or diabetes. To date, the influence of glucose on magnesium degradation has not yet been elucidated, this issue requires more attention. Herein, we present pure Mg exhibiting different corrosion responses to saline and Hank's solutions with different glucose contents, and the degradation mechanism of pure Mg in the saline solution with glucose in comparison with mannitol as a control. On one hand, the corrosion rate of pure Mg increases with the glucose concentration in saline solutions. Glucose rapidly transforms into gluconic acid, which attacks the oxides of the metal and decreases the pH of the solution; it also promotes the absorption of chloride ions on the Mg surface and consequently accelerates corrosion. On the other hand, better corrosion resistance is obtained with increasing glucose content in Hank's solution due to the fact that glucose coordinates Ca2+ ions in Hank's solution and thus improves the formation of Ca-P compounds on the pure Mg surface. This finding will open up new avenues for research on the biodegradation of bio-Mg materials in general, which could yield many new and interesting results.
部门归属	[zeng, rong-chang ; li, xiao-ting ; li, shuo-qi ; zhang, fen] shandong univ sci & technol, coll mat sci & engn, qingdao 266590, peoples r china ; [zeng, rong-chang ; li, xiao-ting ; li, shuo-qi ; zhang, fen] shandong univ sci & technol, state key lab min disaster prevent & control, shandong prov & minist sci & technol, qingdao 266590, peoples r china ; [han, en-hou] chinese acad sci, inst met res, natl engn ctr corros control, shenyang 110016, peoples r china
资助者	National Natural Science Foundation of China [51241001]; SDUST Research Fund [2014TDJH104]; Joint Innovative Center for Safe and Effective Mining Technology and Equipment of Coal Resources; Shandong Province
收录类别	sci
语种	英语
WOS记录号	WOS:000359374500003
引用统计	被引频次：113[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/74910
专题	中国科学院金属研究所
通讯作者	rczeng@foxmail.com
推荐引用方式 GB/T 7714	Zeng, Rong-Chang,Li, Xiao-Ting,Li, Shuo-Qi,et al. In vitro degradation of pure Mg in response to glucose[J]. SCIENTIFIC REPORTS,2015,5:-.
APA	Zeng, Rong-Chang,Li, Xiao-Ting,Li, Shuo-Qi,Zhang, Fen,Han, En-Hou,&rczeng@foxmail.com.(2015).In vitro degradation of pure Mg in response to glucose.SCIENTIFIC REPORTS,5,-.
MLA	Zeng, Rong-Chang,et al."In vitro degradation of pure Mg in response to glucose".SCIENTIFIC REPORTS 5(2015):-.