|Inhibition of Staphylococcus aureus biofilm by a copper-bearing 317L-Cu stainless steel and its corrosion resistance|
|Sun, D; Xu, DK; Yang, CG; Chen, J; Shahzad, MB; Sun, ZQ; Zhao, JL; Gu, TY; Yang, K; Wang, GX; Wang, GX (reprint author), Chongqing Univ, Key Lab Biorheol Sci & Technol, State & Local Joint Engn Lab Vasc Implants, Minist Educ,Bioengn Coll, Chongqing 400030, Peoples R China.; Xu, DK (reprint author), Chinese Acad Sci, Inst Met Res, 72 Wenhua Rd, Shenyang 110016, Peoples R China.
|Source Publication||MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
|Abstract||The present study investigated the antibacterial performance, corrosion resistance and surface properties of antibacterial austenitic 317L-Cu stainless steel (317L-Cu SS). After 4.5 wt% copper was added to 317L stainless steel (317L SS), the new alloy underwent solid solution and aging heat treatment. Fluorescent staining using 4',6-diamidino-2-phenylindole (DAPI) revealed that the 317L-Cu SS showed strong antibacterial efficacy, achieving a 99% inhibition rate of sessile Staphylococcus aureus cells after 5 days. The corrosion data obtained by potentio-dynamic polarization curves indicated that in comparison with 317L SS, the pitting potential and corrosion current density of 317L-Cu slightly decreased due to the addition of Cu. The 317L-Cu SS exhibited no cytotoxicity against zebrafish (Danio rerio) embryos. The experimental results in this study demonstrated that the new alloy has potential applications in medical and daily uses. (C) 2016 Elsevier B.V. All rights reserved.|
; chen, jia
; wang, guixue] chongqing univ, key lab biorheol sci & technol, state & local joint engn lab vasc implants, minist educ,bioengn coll, chongqing 400030, peoples r china
; [xu, dake
; yang, chunguang
; shahzad, m. babar
; sun, ziqing
; zhao, jinlong
; yang, ke] chinese acad sci, inst met res, 72 wenhua rd, shenyang 110016, peoples r china
; [gu, tingyue] ohio univ, inst corros & multiphase technol, dept chem & biomol engn, athens, oh 45701 usa
|Subject Area||Materials Science, bioMaterials
|Funding Organization||National Natural Science Foundation of China [11332003, 31370949, 81400329]; National Key Research and Development Program [2016YFC1102305]; "Young Merit Scholars" program of the Institute of Metal Research, Chinese Academy of Sciences; Chongqing Engineering Laboratory in Vascular Implants; National "111 Plan" Base [B06023]; Public Experiment Center of the State Bioindustrial Base (Chongqing) of China
|Corresponding Author||Wang, GX (reprint author), Chongqing Univ, Key Lab Biorheol Sci & Technol, State & Local Joint Engn Lab Vasc Implants, Minist Educ,Bioengn Coll, Chongqing 400030, Peoples R China.; Xu, DK (reprint author), Chinese Acad Sci, Inst Met Res, 72 Wenhua Rd, Shenyang 110016, Peoples R China.|
Sun, D,Xu, DK,Yang, CG,et al. Inhibition of Staphylococcus aureus biofilm by a copper-bearing 317L-Cu stainless steel and its corrosion resistance[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2016,69:744-750.
Sun, D.,Xu, DK.,Yang, CG.,Chen, J.,Shahzad, MB.,...&Xu, DK .(2016).Inhibition of Staphylococcus aureus biofilm by a copper-bearing 317L-Cu stainless steel and its corrosion resistance.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,69,744-750.
Sun, D,et al."Inhibition of Staphylococcus aureus biofilm by a copper-bearing 317L-Cu stainless steel and its corrosion resistance".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 69(2016):744-750.
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