IMR OpenIR
Antimicrobial Cu-bearing stainless steel scaffolds
Wang, Q; Ren, L; Li, XP; Zhang, SY; Sercombe, TB; Yang, K; Wang, Q (reprint author), China Med Univ, Sch Stomatol, Shenyang 110002, Peoples R China.; Yang, K (reprint author), Chinese Acad Sci, Inst Met Res, Beijing 100864, Peoples R China.; Sercombe, TB (reprint author), Univ Western Australia, Sch Mech & Chem Engn, Nedlands, WA 6009, Australia.
2016-11-01
Source PublicationMATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
ISSN0928-4931
Volume68Pages:519-522
AbstractCopper-bearing stainless steel scaffolds with two different structures (Body Centered Cubic and Gyroid labyrinth) at two solid fractions (25% and 40%) were fabricated from both 316L powder and a mixture of 316L and elemental Cu powder using selective laser melting, and relative 316L scaffolds were served as control group. After processing, the antimicrobial testing demonstrated that the 316L-Cu scaffolds presented excellent antimicrobial activity against Escherichia coli and Staphylococcus aureus, and the cell viability assay indicated that there was no cytotoxic effect of 316L-Cu scaffolds on rat marrow mesenchymal stem cells. As such, these have the potential to reduce implant-associated infections. The Cu was also found to homogeneously distribute within the microstructure by scanning electronic microcopy. The addition of Cu would not significantly affect its strength and stiffness compared to 316L scaffold, and the stiffness of all the scaffolds (3-20GPa) is similar to that of bone and much less than that of bulk stainless steel. Consequently, fabrication of such low stiffness porous structures, especially coupled with the addition of antimicrobial Cu, may provide a new direction for medical stainless steels. (C) 2016 Elsevier B.V. All rights reserved.
description.department[wang, qiang] china med univ, sch stomatol, shenyang 110002, peoples r china ; [ren, ling ; zhang, shuyuan ; yang, ke] chinese acad sci, inst met res, beijing 100864, peoples r china ; [li, xiaopeng ; sercombe, timothy b.] univ western australia, sch mech & chem engn, nedlands, wa 6009, australia
Subject AreaMaterials Science, bioMaterials
Funding OrganizationNational Natural Science Foundation [81301329]; Youth Innovation Promotion Association, CAS [2014168]; Liaoning Province Natural Science Foundation [2015021004]; Shenyang National Laboratory for Materials Science [2015021004]
Indexed Bysci
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/76220
Collection中国科学院金属研究所
Corresponding AuthorWang, Q (reprint author), China Med Univ, Sch Stomatol, Shenyang 110002, Peoples R China.; Yang, K (reprint author), Chinese Acad Sci, Inst Met Res, Beijing 100864, Peoples R China.; Sercombe, TB (reprint author), Univ Western Australia, Sch Mech & Chem Engn, Nedlands, WA 6009, Australia.
Recommended Citation
GB/T 7714
Wang, Q,Ren, L,Li, XP,et al. Antimicrobial Cu-bearing stainless steel scaffolds[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2016,68:519-522.
APA Wang, Q.,Ren, L.,Li, XP.,Zhang, SY.,Sercombe, TB.,...&Sercombe, TB .(2016).Antimicrobial Cu-bearing stainless steel scaffolds.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,68,519-522.
MLA Wang, Q,et al."Antimicrobial Cu-bearing stainless steel scaffolds".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 68(2016):519-522.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wang, Q]'s Articles
[Ren, L]'s Articles
[Li, XP]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wang, Q]'s Articles
[Ren, L]'s Articles
[Li, XP]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wang, Q]'s Articles
[Ren, L]'s Articles
[Li, XP]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.