IMR OpenIR
Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber
Wu, Wei; Chen, Jia; Sun, Da; Kong, Xiangjun; Xu, Dake; Wang, Yi; Luo, Li; Zhang, Kun; Xiao, Keshen; Wang, Guixue; Wang, GX (reprint author), Chongqing Univ, Bioengn Coll, State & Local Joint Engn Lab Vasc Implants, Key Lab Biorheol Sci & Technol,Minist Educ, Chongqing 400044, Peoples R China.; Sun, D (reprint author), Wenzhou Univ, Inst Life Sci, Wenzhou 325000, Peoples R China.; Xiao, KS (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China.
2017-12-15
发表期刊ELSEVIER SCIENCE BV
ISSN0167-577X
卷号209页码:562-565
摘要The present study was intended to investigate the antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber (PMF). The PMF was found to exhibit excellent antibacterial performance against methicillin-resistant Staphylococcus aureus and Candida albicans, exceeding 95% when the PMF concentration was higher than 500 mu g mL (-1). MTS analysis was performed to assess the in vitro cytotoxicity of PMF, which showed PMF with a concentration range of 100-1000 mg L (-1) had no significant toxic effects on L929 fibroblast cells. In addition, the in vivo toxicity assay of PMF was studied in zebrafish (Danio rerio) embryos, and the results confirmed little toxicity at effective antibacterial concentration. Hence, PMF was proved to be a potential coating or filling material with promising antibacterial performance for in implantable medical devices. (c) 2017 Elsevier B.V. All rights reserved.; The present study was intended to investigate the antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber (PMF). The PMF was found to exhibit excellent antibacterial performance against methicillin-resistant Staphylococcus aureus and Candida albicans, exceeding 95% when the PMF concentration was higher than 500 mu g mL (-1). MTS analysis was performed to assess the in vitro cytotoxicity of PMF, which showed PMF with a concentration range of 100-1000 mg L (-1) had no significant toxic effects on L929 fibroblast cells. In addition, the in vivo toxicity assay of PMF was studied in zebrafish (Danio rerio) embryos, and the results confirmed little toxicity at effective antibacterial concentration. Hence, PMF was proved to be a potential coating or filling material with promising antibacterial performance for in implantable medical devices. (c) 2017 Elsevier B.V. All rights reserved.
部门归属[wu, wei ; chen, jia ; wang, yi ; luo, li ; zhang, kun ; wang, guixue] chongqing univ, bioengn coll, state & local joint engn lab vasc implants, key lab biorheol sci & technol,minist educ, chongqing 400044, peoples r china ; [chen, jia] sichuan acad med sci & sichuan prov peoples hosp, inst lab anim, chengdu 610000, sichuan, peoples r china ; [sun, da] wenzhou univ, inst life sci, wenzhou 325000, peoples r china ; [kong, xiangjun] univ macau, state key lab qual res chinese med, inst chinese med sci, macau 999078, peoples r china ; [xu, dake ; xiao, keshen] chinese acad sci, inst met res, shenyang 110016, liaoning, peoples r china
关键词Biomaterials Nanoparticles Phosphorous-magnesium Fiber Antibacterial Performance Zebrafish
学科领域Materials Science, Multidisciplinary ; Physics, Applied
资助者National Natural Science Foundation of China [11332003, 31370949, 81400329, 51603023]; National Key Research and Development Program [2016YFC1102305]; Fundamental Research Funds for the Central Universities [106112016CDJXY230002, 106112016CDJXY230001]; China Postdoctoral Science Foundation [2016M602656, 2017T100682]; Chongqing Postdoctoral Scientific Research Foundation [Xm2016011]; Chongqing Research Program of Basic research and Frontier Technology [cstc2017jcyjAX0186]; Chongqing Engineering Laboratory in Vascular Implants; Public Experiment Center of State Bioindustrial Base (Chongqing)
收录类别SCI
语种英语
文献类型期刊论文
条目标识符http://ir.imr.ac.cn/handle/321006/78932
专题中国科学院金属研究所
通讯作者Wang, GX (reprint author), Chongqing Univ, Bioengn Coll, State & Local Joint Engn Lab Vasc Implants, Key Lab Biorheol Sci & Technol,Minist Educ, Chongqing 400044, Peoples R China.; Sun, D (reprint author), Wenzhou Univ, Inst Life Sci, Wenzhou 325000, Peoples R China.; Xiao, KS (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China.
推荐引用方式
GB/T 7714
Wu, Wei,Chen, Jia,Sun, Da,et al. Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber[J]. ELSEVIER SCIENCE BV,2017,209:562-565.
APA Wu, Wei.,Chen, Jia.,Sun, Da.,Kong, Xiangjun.,Xu, Dake.,...&Xiao, KS .(2017).Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber.ELSEVIER SCIENCE BV,209,562-565.
MLA Wu, Wei,et al."Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber".ELSEVIER SCIENCE BV 209(2017):562-565.
条目包含的文件
条目无相关文件。
个性服务
推荐该条目
保存到收藏夹
查看访问统计
导出为Endnote文件
谷歌学术
谷歌学术中相似的文章
[Wu, Wei]的文章
[Chen, Jia]的文章
[Sun, Da]的文章
百度学术
百度学术中相似的文章
[Wu, Wei]的文章
[Chen, Jia]的文章
[Sun, Da]的文章
必应学术
必应学术中相似的文章
[Wu, Wei]的文章
[Chen, Jia]的文章
[Sun, Da]的文章
相关权益政策
暂无数据
收藏/分享
所有评论 (0)
暂无评论
 

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。