IMR OpenIR
Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber
Wu, Wei; Chen, Jia; Sun, Da; Kong, Xiangjun; Xu, Dake; Wang, Yi; Luo, Li; Zhang, Kun; Xiao, Keshen; Wang, Guixue; Wang, GX (reprint author), Chongqing Univ, Bioengn Coll, State & Local Joint Engn Lab Vasc Implants, Key Lab Biorheol Sci & Technol,Minist Educ, Chongqing 400044, Peoples R China.; Sun, D (reprint author), Wenzhou Univ, Inst Life Sci, Wenzhou 325000, Peoples R China.; Xiao, KS (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China.
2017-12-15
Source PublicationELSEVIER SCIENCE BV
ISSN0167-577X
Volume209Pages:562-565
AbstractThe present study was intended to investigate the antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber (PMF). The PMF was found to exhibit excellent antibacterial performance against methicillin-resistant Staphylococcus aureus and Candida albicans, exceeding 95% when the PMF concentration was higher than 500 mu g mL (-1). MTS analysis was performed to assess the in vitro cytotoxicity of PMF, which showed PMF with a concentration range of 100-1000 mg L (-1) had no significant toxic effects on L929 fibroblast cells. In addition, the in vivo toxicity assay of PMF was studied in zebrafish (Danio rerio) embryos, and the results confirmed little toxicity at effective antibacterial concentration. Hence, PMF was proved to be a potential coating or filling material with promising antibacterial performance for in implantable medical devices. (c) 2017 Elsevier B.V. All rights reserved.; The present study was intended to investigate the antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber (PMF). The PMF was found to exhibit excellent antibacterial performance against methicillin-resistant Staphylococcus aureus and Candida albicans, exceeding 95% when the PMF concentration was higher than 500 mu g mL (-1). MTS analysis was performed to assess the in vitro cytotoxicity of PMF, which showed PMF with a concentration range of 100-1000 mg L (-1) had no significant toxic effects on L929 fibroblast cells. In addition, the in vivo toxicity assay of PMF was studied in zebrafish (Danio rerio) embryos, and the results confirmed little toxicity at effective antibacterial concentration. Hence, PMF was proved to be a potential coating or filling material with promising antibacterial performance for in implantable medical devices. (c) 2017 Elsevier B.V. All rights reserved.
description.department[wu, wei ; chen, jia ; wang, yi ; luo, li ; zhang, kun ; wang, guixue] chongqing univ, bioengn coll, state & local joint engn lab vasc implants, key lab biorheol sci & technol,minist educ, chongqing 400044, peoples r china ; [chen, jia] sichuan acad med sci & sichuan prov peoples hosp, inst lab anim, chengdu 610000, sichuan, peoples r china ; [sun, da] wenzhou univ, inst life sci, wenzhou 325000, peoples r china ; [kong, xiangjun] univ macau, state key lab qual res chinese med, inst chinese med sci, macau 999078, peoples r china ; [xu, dake ; xiao, keshen] chinese acad sci, inst met res, shenyang 110016, liaoning, peoples r china
KeywordBiomaterials Nanoparticles Phosphorous-magnesium Fiber Antibacterial Performance Zebrafish
Subject AreaMaterials Science, Multidisciplinary ; Physics, Applied
Funding OrganizationNational Natural Science Foundation of China [11332003, 31370949, 81400329, 51603023]; National Key Research and Development Program [2016YFC1102305]; Fundamental Research Funds for the Central Universities [106112016CDJXY230002, 106112016CDJXY230001]; China Postdoctoral Science Foundation [2016M602656, 2017T100682]; Chongqing Postdoctoral Scientific Research Foundation [Xm2016011]; Chongqing Research Program of Basic research and Frontier Technology [cstc2017jcyjAX0186]; Chongqing Engineering Laboratory in Vascular Implants; Public Experiment Center of State Bioindustrial Base (Chongqing)
Indexed BySCI
Language英语
WOS IDWOS:000413124300143
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/78932
Collection中国科学院金属研究所
Corresponding AuthorWang, GX (reprint author), Chongqing Univ, Bioengn Coll, State & Local Joint Engn Lab Vasc Implants, Key Lab Biorheol Sci & Technol,Minist Educ, Chongqing 400044, Peoples R China.; Sun, D (reprint author), Wenzhou Univ, Inst Life Sci, Wenzhou 325000, Peoples R China.; Xiao, KS (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China.
Recommended Citation
GB/T 7714
Wu, Wei,Chen, Jia,Sun, Da,et al. Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber[J]. ELSEVIER SCIENCE BV,2017,209:562-565.
APA Wu, Wei.,Chen, Jia.,Sun, Da.,Kong, Xiangjun.,Xu, Dake.,...&Xiao, KS .(2017).Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber.ELSEVIER SCIENCE BV,209,562-565.
MLA Wu, Wei,et al."Study on antibacterial performance and biocompatibility of a novel phosphorus-magnesium fiber".ELSEVIER SCIENCE BV 209(2017):562-565.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Wu, Wei]'s Articles
[Chen, Jia]'s Articles
[Sun, Da]'s Articles
Baidu academic
Similar articles in Baidu academic
[Wu, Wei]'s Articles
[Chen, Jia]'s Articles
[Sun, Da]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Wu, Wei]'s Articles
[Chen, Jia]'s Articles
[Sun, Da]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.