In vitro study on infectious ureteral encrustation resistance of Cu-bearing stainless steel

IMR OpenIR

	In vitro study on infectious ureteral encrustation resistance of Cu-bearing stainless steel
	Zhao, Jing; Ren, Ling; Zhang, Bingchun; Cao, Zhiqiang; Yang, Ke; Ren, L; Yang, K (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China.
	2017-12-01
发表期刊	JOURNAL MATER SCI TECHNOL
ISSN	1005-0302
卷号	33 期号:12 页码:1604-1609
摘要	Cu-bearing stainless steel has been found to have obvious inhibition performance against encrustation in vitro. This study was aiming to further investigate the inhibitory effect of a Cu-bearing stainless steel (316L-Cu SS) on the infectious encrustation based on its antimicrobial activity. The encrustation in presence of bacteria, antibacterial performance, urease production and Ca and Mg precipitation were examined by scanning electron microscopy, antibacterial assay, enzyme-linked immunosorbent assay and inductively coupled plasma-mass spectrometry, respectively. It was found that 316L-Cu SS could inhibit the formation of bacterial biofilm due to the release of Cu2+ ions and then decrease the urease amount splitting by bacteria, which produced a neutral environment with pH around 7. However, more encrustations coupled with bacterial biofilms on the surface of comparison stainless steel (316L SS) with an alkaline environment were recorded. It can thus be seen that the 316L-Cu SS highlights prominent superiority against encrustation in the presence of microorganisms. (C) 2017 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.; Cu-bearing stainless steel has been found to have obvious inhibition performance against encrustation in vitro. This study was aiming to further investigate the inhibitory effect of a Cu-bearing stainless steel (316L-Cu SS) on the infectious encrustation based on its antimicrobial activity. The encrustation in presence of bacteria, antibacterial performance, urease production and Ca and Mg precipitation were examined by scanning electron microscopy, antibacterial assay, enzyme-linked immunosorbent assay and inductively coupled plasma-mass spectrometry, respectively. It was found that 316L-Cu SS could inhibit the formation of bacterial biofilm due to the release of Cu2+ ions and then decrease the urease amount splitting by bacteria, which produced a neutral environment with pH around 7. However, more encrustations coupled with bacterial biofilms on the surface of comparison stainless steel (316L SS) with an alkaline environment were recorded. It can thus be seen that the 316L-Cu SS highlights prominent superiority against encrustation in the presence of microorganisms. (C) 2017 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.
部门归属	[zhao, jing ; ren, ling ; zhang, bingchun ; yang, ke] chinese acad sci, inst met res, shenyang 110016, liaoning, peoples r china ; [zhao, jing] chinese acad sci, grad sch, beijing 100049, peoples r china ; [cao, zhiqiang] gen hosp shenyang mil reg, shenyang 110840, liaoning, peoples r china
关键词	316l Cu-bearing Stainless Steel Infectious Encrustation S. Aureus Urease Ph
学科领域	Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
资助者	National Basic Research Program of China (973 Program) [2012CB619101]; National Natural Science Foundation of China [51171186, 51371168]; Foundation of Jiangsu Collaborative Innovation Center of Biomedical Functional Materials
收录类别	SCI
语种	英语
WOS记录号	WOS:000418646000020
引用统计	被引频次：17[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/78942
专题	中国科学院金属研究所
通讯作者	Ren, L; Yang, K (reprint author), Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China.
推荐引用方式 GB/T 7714	Zhao, Jing,Ren, Ling,Zhang, Bingchun,et al. In vitro study on infectious ureteral encrustation resistance of Cu-bearing stainless steel[J]. JOURNAL MATER SCI TECHNOL,2017,33(12):1604-1609.
APA	Zhao, Jing.,Ren, Ling.,Zhang, Bingchun.,Cao, Zhiqiang.,Yang, Ke.,...&Yang, K .(2017).In vitro study on infectious ureteral encrustation resistance of Cu-bearing stainless steel.JOURNAL MATER SCI TECHNOL,33(12),1604-1609.
MLA	Zhao, Jing,et al."In vitro study on infectious ureteral encrustation resistance of Cu-bearing stainless steel".JOURNAL MATER SCI TECHNOL 33.12(2017):1604-1609.