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pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition
Feng, LJ; Yang, HY; Dong, XQ; Lei, HB; Chen, D; Feng, LJ (reprint author), Weifang Univ Sci & Technol, Shandong Peninsula Blue Econ & Engn Res Inst, Shouguang 262700, Weifang, Peoples R China.
2018-02-20
Source PublicationJOURNAL OF APPLIED POLYMER SCIENCE
ISSN0021-8995
Volume135Issue:8Pages:-
AbstractThe waste problem of the rebar inhibitors is very serious due to that it is a long time before they can exert their best effect in the concrete and they are kept losing all the time. However, there is still no effective solution to alleviate such situation. Meanwhile, drug delivery control technology based on environmental sensitive polymers has been successfully applied in biomedical fields. Thus, poly(acrylicacid)-acrylamide was synthesized as smart carrier for controlling rebar inhibitors delivery in concrete. Dipotassium hydrogen phosphate as model drug was encapsulated inside the polymeric particles via a self-assembly process. The pH-responsive activities of the polymeric particles were estimated by monitoring their swelling performances in solutions of different pH values and the drug delivery control characteristics were studied in simulated concrete pore solutions. The results indicate the polymeric particles deserve network structures with high porosity and exhibit excellent pH-responsive activities, which can perform as perfect intelligent carriers whereas the releasing of the inhibitors follows the first-order kinetic law. The work suggests a new application field of drug delivery control technology. (C) 2017 Wiley Periodicals, Inc.; The waste problem of the rebar inhibitors is very serious due to that it is a long time before they can exert their best effect in the concrete and they are kept losing all the time. However, there is still no effective solution to alleviate such situation. Meanwhile, drug delivery control technology based on environmental sensitive polymers has been successfully applied in biomedical fields. Thus, poly(acrylicacid)-acrylamide was synthesized as smart carrier for controlling rebar inhibitors delivery in concrete. Dipotassium hydrogen phosphate as model drug was encapsulated inside the polymeric particles via a self-assembly process. The pH-responsive activities of the polymeric particles were estimated by monitoring their swelling performances in solutions of different pH values and the drug delivery control characteristics were studied in simulated concrete pore solutions. The results indicate the polymeric particles deserve network structures with high porosity and exhibit excellent pH-responsive activities, which can perform as perfect intelligent carriers whereas the releasing of the inhibitors follows the first-order kinetic law. The work suggests a new application field of drug delivery control technology. (C) 2017 Wiley Periodicals, Inc.
description.department[feng, lijuan ; dong, xiqing ; lei, haibo ; chen, di] weifang univ sci & technol, shandong peninsula blue econ & engn res inst, shouguang 262700, weifang, peoples r china ; [yang, huaiyu] chinese acad sci, inst met res, state key lab corros & protect, shenyang 110016, liaoning, peoples r china
KeywordTransfer Radical Polymerization Functionalized Graphene Sheets Comb-like Polymers End-use Evaluation Nanocomposites Adhesive Crystallization Oxide Chemistry Mechanism
Subject AreaPolymer Science
Funding OrganizationProject of Shandong Province Higher Educational Science and Technology Program [J15LA62]; Distinguished Middle-Aged and Young Scientist Encourage and Reward Foundation of Shandong Province [BS2014CL029]
Indexed BySCI
Language英语
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/79492
Collection中国科学院金属研究所
Corresponding AuthorFeng, LJ (reprint author), Weifang Univ Sci & Technol, Shandong Peninsula Blue Econ & Engn Res Inst, Shouguang 262700, Weifang, Peoples R China.
Recommended Citation
GB/T 7714
Feng, LJ,Yang, HY,Dong, XQ,et al. pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2018,135(8):-.
APA Feng, LJ,Yang, HY,Dong, XQ,Lei, HB,Chen, D,&Feng, LJ .(2018).pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition.JOURNAL OF APPLIED POLYMER SCIENCE,135(8),-.
MLA Feng, LJ,et al."pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition".JOURNAL OF APPLIED POLYMER SCIENCE 135.8(2018):-.
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