pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition

IMR OpenIR

	pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition
	Feng, LJ; Yang, HY; Dong, XQ; Lei, HB; Chen, D; Feng, LJ (reprint author), Weifang Univ Sci & Technol, Shandong Peninsula Blue Econ & Engn Res Inst, Shouguang 262700, Weifang, Peoples R China.
	2018-02-20
发表期刊	JOURNAL OF APPLIED POLYMER SCIENCE
ISSN	0021-8995
卷号	135 期号:8 页码:-
摘要	The waste problem of the rebar inhibitors is very serious due to that it is a long time before they can exert their best effect in the concrete and they are kept losing all the time. However, there is still no effective solution to alleviate such situation. Meanwhile, drug delivery control technology based on environmental sensitive polymers has been successfully applied in biomedical fields. Thus, poly(acrylicacid)-acrylamide was synthesized as smart carrier for controlling rebar inhibitors delivery in concrete. Dipotassium hydrogen phosphate as model drug was encapsulated inside the polymeric particles via a self-assembly process. The pH-responsive activities of the polymeric particles were estimated by monitoring their swelling performances in solutions of different pH values and the drug delivery control characteristics were studied in simulated concrete pore solutions. The results indicate the polymeric particles deserve network structures with high porosity and exhibit excellent pH-responsive activities, which can perform as perfect intelligent carriers whereas the releasing of the inhibitors follows the first-order kinetic law. The work suggests a new application field of drug delivery control technology. (C) 2017 Wiley Periodicals, Inc.; The waste problem of the rebar inhibitors is very serious due to that it is a long time before they can exert their best effect in the concrete and they are kept losing all the time. However, there is still no effective solution to alleviate such situation. Meanwhile, drug delivery control technology based on environmental sensitive polymers has been successfully applied in biomedical fields. Thus, poly(acrylicacid)-acrylamide was synthesized as smart carrier for controlling rebar inhibitors delivery in concrete. Dipotassium hydrogen phosphate as model drug was encapsulated inside the polymeric particles via a self-assembly process. The pH-responsive activities of the polymeric particles were estimated by monitoring their swelling performances in solutions of different pH values and the drug delivery control characteristics were studied in simulated concrete pore solutions. The results indicate the polymeric particles deserve network structures with high porosity and exhibit excellent pH-responsive activities, which can perform as perfect intelligent carriers whereas the releasing of the inhibitors follows the first-order kinetic law. The work suggests a new application field of drug delivery control technology. (C) 2017 Wiley Periodicals, Inc.
部门归属	[feng, lijuan ; dong, xiqing ; lei, haibo ; chen, di] weifang univ sci & technol, shandong peninsula blue econ & engn res inst, shouguang 262700, weifang, peoples r china ; [yang, huaiyu] chinese acad sci, inst met res, state key lab corros & protect, shenyang 110016, liaoning, peoples r china
关键词	Transfer Radical Polymerization Functionalized Graphene Sheets Comb-like Polymers End-use Evaluation Nanocomposites Adhesive Crystallization Oxide Chemistry Mechanism
学科领域	Polymer Science
资助者	Project of Shandong Province Higher Educational Science and Technology Program [J15LA62]; Distinguished Middle-Aged and Young Scientist Encourage and Reward Foundation of Shandong Province [BS2014CL029]
收录类别	SCI
语种	英语
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/79492
专题	中国科学院金属研究所
通讯作者	Feng, LJ (reprint author), Weifang Univ Sci & Technol, Shandong Peninsula Blue Econ & Engn Res Inst, Shouguang 262700, Weifang, Peoples R China.
推荐引用方式 GB/T 7714	Feng, LJ,Yang, HY,Dong, XQ,et al. pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition[J]. JOURNAL OF APPLIED POLYMER SCIENCE,2018,135(8):-.
APA	Feng, LJ,Yang, HY,Dong, XQ,Lei, HB,Chen, D,&Feng, LJ .(2018).pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition.JOURNAL OF APPLIED POLYMER SCIENCE,135(8),-.
MLA	Feng, LJ,et al."pH-sensitive polymeric particles as smart carriers for rebar inhibitors delivery in alkaline condition".JOURNAL OF APPLIED POLYMER SCIENCE 135.8(2018):-.