IMR OpenIR
In vitro study on cytocompatibility and osteogenesis ability of Ti-Cu alloy
Liu, Rui; Ma, Zheng; Kolawole, Sharafadeen Kunle; Zeng, Lilan; Zhao, Ying; Ren, Ling; Yang, Ke
2019-07-01
Source PublicationJOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
ISSN0957-4530
Volume30Issue:7
AbstractTitanium implants easily suffer bacteria-related infections in clinic due to their inherent lack of self-protection ability. Therefore, a novel Ti-Cu alloy with good antibacterial activity has been developed as a new kind of implant material. This study focuses on a systematic evaluation of both cytocompatibility and osteogenesis activity of the Ti-Cu alloy in vitro. It was revealed that an addition of 5% Cu into pure Ti would not cause any negative effect on osteoblasts adhesion, proliferation and apoptosis cultured with Ti-Cu alloy. In addition, Ti-Cu alloy could significantly promote the osteogenic differentiation of MG 63 cells by upregulating the osteogenesis-related gene expressions including alkaline phosphatase (ALP), Collagen I (Colla I), osteopontin (OPN) and osteocalcin (OCN). These promising results suggest that the Ti-Cu alloy has great potential to be used as a multi-functional titanium implant for clinical applications. [GRAPHICS]
Indexed BySCI
Language英语
WOS IDWOS:000472211800003
PublisherSPRINGER
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/80945
Collection中国科学院金属研究所
Recommended Citation
GB/T 7714
Liu, Rui,Ma, Zheng,Kolawole, Sharafadeen Kunle,et al. In vitro study on cytocompatibility and osteogenesis ability of Ti-Cu alloy[J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,2019,30(7).
APA Liu, Rui.,Ma, Zheng.,Kolawole, Sharafadeen Kunle.,Zeng, Lilan.,Zhao, Ying.,...&Yang, Ke.(2019).In vitro study on cytocompatibility and osteogenesis ability of Ti-Cu alloy.JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE,30(7).
MLA Liu, Rui,et al."In vitro study on cytocompatibility and osteogenesis ability of Ti-Cu alloy".JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE 30.7(2019).
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu, Rui]'s Articles
[Ma, Zheng]'s Articles
[Kolawole, Sharafadeen Kunle]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu, Rui]'s Articles
[Ma, Zheng]'s Articles
[Kolawole, Sharafadeen Kunle]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu, Rui]'s Articles
[Ma, Zheng]'s Articles
[Kolawole, Sharafadeen Kunle]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.