Experimental study of in vivo implantation of a magnesium alloy at early stage

IMR OpenIR

	Experimental study of in vivo implantation of a magnesium alloy at early stage
	Zhang Guangdao 1; Huang Jingjing 2; Yang Ke 2; Zhang Bingchun 2; Ai Hongjun 1
通讯作者	Ai Hongjun(aih0620@yahoo.com.cn)
	2007-11-01
发表期刊	ACTA METALLURGICA SINICA
ISSN	0412-1961
卷号	43 期号:11 页码:1186-1190
摘要	In order to study both the effect and the degradation behavior of magnesium alloys on/in animals, AZ31B magnesium alloys with different dimensions were implanted in the New-Zealand rabbits, and compared with a titanium alloy (Ti-6Al-4V) as a control material. It was found from the experiments that the osteotylus was formed surround the magnesium alloy implant after 2 weeks, which was turned into ripe bone tissue after 8 weeks. The implantation of the magnesium alloy did not show negative influence on the recirculating, immune and urinary systems of the rabbits. Magnesium calcium apatite, which was the main degradation product of the magnesium alloy, could be metabolismed by the kidney. Magnesium ion concentration in the blood was in the range of normal values. It can be concluded that the magnesium alloy implantation is safe for rabbits at the early stage, and the implant can be beneficial to the new bone formation.
关键词	metal based biomaterial magnesium alloy absorbable material bone
收录类别	SCI
语种	英语
WOS研究方向	Metallurgy & Metallurgical Engineering
WOS类目	Metallurgy & Metallurgical Engineering
WOS记录号	WOS:000251576700012
出版者	SCIENCE CHINA PRESS
引用统计	被引频次：30[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/90850
专题	中国科学院金属研究所
通讯作者	Ai Hongjun
作者单位	1.Chinese Med Univ, Sch Stomatol, Shenyang 110002, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Zhang Guangdao,Huang Jingjing,Yang Ke,et al. Experimental study of in vivo implantation of a magnesium alloy at early stage[J]. ACTA METALLURGICA SINICA,2007,43(11):1186-1190.
APA	Zhang Guangdao,Huang Jingjing,Yang Ke,Zhang Bingchun,&Ai Hongjun.(2007).Experimental study of in vivo implantation of a magnesium alloy at early stage.ACTA METALLURGICA SINICA,43(11),1186-1190.
MLA	Zhang Guangdao,et al."Experimental study of in vivo implantation of a magnesium alloy at early stage".ACTA METALLURGICA SINICA 43.11(2007):1186-1190.