Biocompatibility of CA-P/AZ31B Magnesium Alloy

IMR OpenIR

	Biocompatibility of CA-P/AZ31B Magnesium Alloy
	Guo Lei 1; Liu Kui 1; Zhang Shiliang 1; Gao Xiaoyu 1; Huang Jingjing 2; Yang Ke 2
通讯作者	Guo Lei(g572@sina.com)
	2009
发表期刊	RARE METAL MATERIALS AND ENGINEERING
ISSN	1002-185X
卷号	38 期号:1 页码:99-103
摘要	The AZ31B magnesium alloy coated with calcium phosphate (CA-P/AZ31B) was implanted in rabbit skeletal and muscular tissue in this study. The inflammatory reaction in skeletal and muscular tissue was observed around the magnesium alloy in vivo. The microstructure and cytotoxic effect of the magnesium alloy were detected. The results show that the release and degradation process of AZ31B magnesium alloy was efficiently delayed by coated with CA-P. The surface roughness of AZ31B magnesium alloy was raised by coated with CA-P, whereas the inflammation induced by AZ31B magnesium alloy was inhibited in vivo. By hemolysis tests, the hemolytic effect was significantly decreased for the CA-P/AZ31B magnesium alloy coated with CA-P. Therefore, the alloy would be a new generation of degradable and biocompatible materials for medical applications.
关键词	magnesium alloy calcium phosphate biocompatibility inflammation
收录类别	SCI
语种	英语
WOS研究方向	Materials Science ; Metallurgy & Metallurgical Engineering
WOS类目	Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS记录号	WOS:000262955600023
出版者	NORTHWEST INST NONFERROUS METAL RESEARCH
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/96934
专题	中国科学院金属研究所
通讯作者	Guo Lei
作者单位	1.China Med Univ, Affiliated Hosp 1, Dept Orthoped Surg, Shenyang 110001, Peoples R China 2.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China
推荐引用方式 GB/T 7714	Guo Lei,Liu Kui,Zhang Shiliang,et al. Biocompatibility of CA-P/AZ31B Magnesium Alloy[J]. RARE METAL MATERIALS AND ENGINEERING,2009,38(1):99-103.
APA	Guo Lei,Liu Kui,Zhang Shiliang,Gao Xiaoyu,Huang Jingjing,&Yang Ke.(2009).Biocompatibility of CA-P/AZ31B Magnesium Alloy.RARE METAL MATERIALS AND ENGINEERING,38(1),99-103.
MLA	Guo Lei,et al."Biocompatibility of CA-P/AZ31B Magnesium Alloy".RARE METAL MATERIALS AND ENGINEERING 38.1(2009):99-103.