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Ligand-Based Structural Optimization of Grb2-SH2 Inhibitors: High Affinity, Low Charge and Reduced Peptidic Nature 期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2011, 卷号: 31, 期号: 12, 页码: 2019-2033
作者:  Peng Dian;  Zhi Ying;  Xue Ting;  Gao Huiyuan;  Long Yaqiu
收藏  |  浏览/下载:95/0  |  提交时间:2021/02/02
STRUCTURE-BASED DESIGN  RING-CLOSING METATHESIS  SH2 DOMAIN  NONPHOSPHORYLATED INHIBITOR  PHOSPHOTYROSYL MIMETICS  ACID-RESIDUES  BINDING  ANTAGONISTS  POSITION  REQUIREMENTS  phosphotyrosine  Grb2-SH2 inhibitor  structure-activity relationship  mitogenic ras pathway  anti-tumor drug  
Theoretical investigation of ductilizing effects of alloying elements on TiAl 期刊论文
Intermetallics, 1998, 卷号: 6, 期号: 3, 页码: 157-165
作者:  Y. Song;  D. S. Xu;  R. Yang;  D. Li;  Z. Q. Hu
收藏  |  浏览/下载:72/0  |  提交时间:2012/04/14
Titanium Aluminides  Based On Tial  Alloy Design  Electronic Structure  Of Metals And Alloys  Electronic Structure  Calculation  Deformation-behavior  Base Alloys  Compound  Phase  Cr  Dissociation  Temperature  Transition  Mechanisms  Additions