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Tanshinone IIA alleviates blast -induced inflammation, oxidative stress and apoptosis in mice partly by inhibiting the PI3K/Akt/FoxO1 signaling pathway 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 152, 页码: 52-60
Authors:  Liu, Yunen;  Tong, Changci;  Tang, Yushan;  Cong, Peifang;  Liu, Ying;  Shi, Xiuyun;  Shi, Lin;  Zhao, Yan;  Jin, Hongxu;  Li, Jing;  Hou, Mingxiao
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Blast injury  Tan IIA  Acute lung injury  Oxidative stress  Inflammation  PI3K  Akt  FoxO1 signaling pathway  
Tanshinone IIA alleviates blast -induced inflammation, oxidative stress and apoptosis in mice partly by inhibiting the PI3K/Akt/FoxO1 signaling pathway 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2020, 卷号: 152, 页码: 52-60
Authors:  Liu, Yunen;  Tong, Changci;  Tang, Yushan;  Cong, Peifang;  Liu, Ying;  Shi, Xiuyun;  Shi, Lin;  Zhao, Yan;  Jin, Hongxu;  Li, Jing;  Hou, Mingxiao
Favorite  |  View/Download:94/0  |  Submit date:2021/02/02
Blast injury  Tan IIA  Acute lung injury  Oxidative stress  Inflammation  PI3K  Akt  FoxO1 signaling pathway  
CD28 Deficiency Ameliorates Thoracic Blast Exposure-Induced Oxidative Stress and Apoptosis in the Brain through the PI3K/Nrf2/Keap1 Signaling Pathway 期刊论文
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2019, 卷号: 2019, 页码: 14
Authors:  Cong, Peifang;  Tong, Changci;  Liu, Ying;  Shi, Lin;  Shi, Xiuyun;  Zhao, Yan;  Xiao, Keshen;  Jin, Hongxu;  Liu, Yunen;  Hou, Mingxiao
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CD28 Deficiency Ameliorates Blast Exposure-Induced Lung Inflammation, Oxidative Stress, Apoptosis, and T Cell Accumulation in the Lungs via the PI3K/Akt/FoxO1 Signaling Pathway 期刊论文
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2019, 卷号: 2019, 页码: 15
Authors:  Liu, Yunen;  Tong, Changci;  Xu, Ying;  Gong, Peifang;  Liu, Ying;  Shi, Lin;  Shi, Xiuyun;  Zhao, Yan;  Bi, Guangyuan;  Jin, Hongxu;  Hou, Mingxiao
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Effect of Matrix Metallopeptidase 13 on the Function of Mouse Bone Marrow-derived Dendritic Cells 期刊论文
CHINESE MEDICAL JOURNAL, 2017, 卷号: 130, 期号: 6, 页码: 717-721
Authors:  Li XiaoDong;  Zhang XinRui;  Li ZhiHao;  Yang Yang;  Zhang Duo;  Zheng Heng;  Dong ShuYing;  Chen Juan;  Zeng XianDong
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METALLOPROTEINASES  MODULATORS  EXPRESSION  MMP-13  Apoptosis  Dendritic Cell  Matrix Metallopeptidase 13  Maturation  Phagocytosis  
Effect of Matrix Metallopeptidase 13 on the Function of Mouse Bone Marrow-derived Dendritic Cells 期刊论文
CHINESE MEDICAL JOURNAL, 2017, 卷号: 130, 期号: 6, 页码: 717-721
Authors:  Li XiaoDong;  Zhang XinRui;  Li ZhiHao;  Yang Yang;  Zhang Duo;  Zheng Heng;  Dong ShuYing;  Chen Juan;  Zeng XianDong
Favorite  |  View/Download:85/0  |  Submit date:2021/02/02
METALLOPROTEINASES  MODULATORS  EXPRESSION  MMP-13  Apoptosis  Dendritic Cell  Matrix Metallopeptidase 13  Maturation  Phagocytosis  
High-dose thalidomide increases the risk of peripheral neuropathy in the treatment of ankylosing spondylitis 期刊论文
Neural Regeneration Research, 2015, 卷号: 10, 期号: 5, 页码: 814-818
Authors:  Xue Hongxia;  Fu Wenyi;  Cui Huadong;  Yang Lili;  Zhang Ning;  Zhao Lijuan
Favorite  |  View/Download:96/0  |  Submit date:2021/02/02
active zone stability  Drosophila  neuromuscular junction  dephosphorylation  Liprin-α  Syd-1  PP2A  GSK-3?  living scaffolds  neural tissue engineering  cell transplant  biomaterials  regeneration  neurotrauma  neurodegeneration  axon pathfinding  cell migration  injury  plasticity  neurodegenerative disease  brain  therapy  neuron  microglia  neural progenitor  tissue engineering  neuroregeneration  repair  central nervous system  biomaterial  regenerative medicine  nanotechnology  spinal cord injury  axonal regeneration  exosome  extracellular vesicle  microRNA  microvesicle  nerve gap  neurite outgrowth  peripheral nerve injury  Schwann cell  stem cell  hemodynamic phases  cerebral subarachnoid hemorrhage  metabolic crises  nerve regeneration  hypoxic-ischemic brain damage  ginsenoside Rg1  neural stem cells  cell transplantation  cell differentiation  cognition  nerve reconstruction  neural regeneration  nerve regeneration  brain injury  neuroimaging  functional magnetic resonance imaging  regional homogeneity  apoplexy  subacute  ischemia  participants  healthy  volunteers  brain activity  NSFC grants  neural regeneration  nerve regeneration  brain injury  neuroprotection  cerebral ischemia/reperfusion injury  lateral intracerebroventricular injection  Apelin-13  nerve apoptosis  Bcl-2  caspase-3  NSFC grants  neural regeneration  nerve regeneration  fractalkine  CX3 chemokine receptor 1  neuronal maturation  dendrites  doublecortin  synaptic maturation  newborn neurons  neural regeneration  nerve regeneration  neurodegenerative diseases  Alzheimer′s disease  transgenic animal models  mice  epimedium herb  milkvetch root  kudzuvine root  divalent metal transporter 1  ferroportin 1  neural regeneration  nerve regeneration  microRNA-124  neurogenesis  neuronal survival  Huntington′s disease  SRY-related HMG box transcription factor 9  brain-derived neurotrophic factor  peroxisome proliferator-activated receptor gamma coactivator 1-alpha  mutant huntingtin  nerve regeneration  Ras/Raf/Erk1/2 signaling pathway  spinal cord injury  apoptosis  repair  regulation  inhibition  neural regeneration  nerve regeneration  neurogenic bladder  bibliometric analysis  Web of Science database  visualization analysis  CiteSpace III  citation analysis  neural regeneration  nerve regeneration  sciatic nerve injury  autologous nerve grafting  epineurial suturing  three-dimensional finite element models  load  stress  displacement  neural regeneration  nerve regeneration  brain injury  facial palsy  Bell′s palsy  comparison  methodological quality  therapy  fixed effect model  acupuncture  incomplete recovery  randomized controlled trials  electroacupuncture  NSFC grants  neural regeneration  nerve regeneration  peripheral nerve injury  thalidomide  ankylosing spondylitis  adverse reactions  peripheral neuropathy  treatment  dose  treatment time  age  sex  neural regeneration  Neurology. Diseases of the nervous system  RC346-429  prospective study  
High-dose thalidomide increases the risk of peripheral neuropathy in the treatment of ankylosing spondylitis 期刊论文
Neural Regeneration Research, 2015, 卷号: 10, 期号: 5, 页码: 814-818
Authors:  Xue Hongxia;  Fu Wenyi;  Cui Huadong;  Yang Lili;  Zhang Ning;  Zhao Lijuan
Favorite  |  View/Download:87/0  |  Submit date:2021/02/02
active zone stability  Drosophila  neuromuscular junction  dephosphorylation  Liprin-α  Syd-1  PP2A  GSK-3?  living scaffolds  neural tissue engineering  cell transplant  biomaterials  regeneration  neurotrauma  neurodegeneration  axon pathfinding  cell migration  injury  plasticity  neurodegenerative disease  brain  therapy  neuron  microglia  neural progenitor  tissue engineering  neuroregeneration  repair  central nervous system  biomaterial  regenerative medicine  nanotechnology  spinal cord injury  axonal regeneration  exosome  extracellular vesicle  microRNA  microvesicle  nerve gap  neurite outgrowth  peripheral nerve injury  Schwann cell  stem cell  hemodynamic phases  cerebral subarachnoid hemorrhage  metabolic crises  nerve regeneration  hypoxic-ischemic brain damage  ginsenoside Rg1  neural stem cells  cell transplantation  cell differentiation  cognition  nerve reconstruction  neural regeneration  nerve regeneration  brain injury  neuroimaging  functional magnetic resonance imaging  regional homogeneity  apoplexy  subacute  ischemia  participants  healthy  volunteers  brain activity  NSFC grants  neural regeneration  nerve regeneration  brain injury  neuroprotection  cerebral ischemia/reperfusion injury  lateral intracerebroventricular injection  Apelin-13  nerve apoptosis  Bcl-2  caspase-3  NSFC grants  neural regeneration  nerve regeneration  fractalkine  CX3 chemokine receptor 1  neuronal maturation  dendrites  doublecortin  synaptic maturation  newborn neurons  neural regeneration  nerve regeneration  neurodegenerative diseases  Alzheimer′s disease  transgenic animal models  mice  epimedium herb  milkvetch root  kudzuvine root  divalent metal transporter 1  ferroportin 1  neural regeneration  nerve regeneration  microRNA-124  neurogenesis  neuronal survival  Huntington′s disease  SRY-related HMG box transcription factor 9  brain-derived neurotrophic factor  peroxisome proliferator-activated receptor gamma coactivator 1-alpha  mutant huntingtin  nerve regeneration  Ras/Raf/Erk1/2 signaling pathway  spinal cord injury  apoptosis  repair  regulation  inhibition  neural regeneration  nerve regeneration  neurogenic bladder  bibliometric analysis  Web of Science database  visualization analysis  CiteSpace III  citation analysis  neural regeneration  nerve regeneration  sciatic nerve injury  autologous nerve grafting  epineurial suturing  three-dimensional finite element models  load  stress  displacement  neural regeneration  nerve regeneration  brain injury  facial palsy  Bell′s palsy  comparison  methodological quality  therapy  fixed effect model  acupuncture  incomplete recovery  randomized controlled trials  electroacupuncture  NSFC grants  neural regeneration  nerve regeneration  peripheral nerve injury  thalidomide  ankylosing spondylitis  adverse reactions  peripheral neuropathy  treatment  dose  treatment time  age  sex  neural regeneration  Neurology. Diseases of the nervous system  RC346-429  prospective study  
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
Authors:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
Favorite  |  View/Download:66/0  |  Submit date:2021/02/02
ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta  
Isoindolone derivative QSN-10c induces leukemic cell apoptosis and suppresses angiogenesis via PI3K/AKT signaling pathway inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 625-635
Authors:  Lv Wenwen;  Qin Sining;  Chen Congqin;  Zhang Jinjie;  Ren Tianshu;  Xu Yongnan;  Zhao Qingchun
Favorite  |  View/Download:130/0  |  Submit date:2021/02/02
ENDOTHELIAL GROWTH-FACTOR  DRUG-INDUCED APOPTOSIS  HEMATOLOGICAL MALIGNANCIES  ACTIN REORGANIZATION  ANTICANCER DRUG  BONE-MARROW  KINASE AKT  CANCER  THALIDOMIDE  MIGRATION  isoindolone  anticancer drug  leukemia  zebrafish  angiogenesis  apoptosis  AKT  GSK3 beta