| Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine | |
| Mohsin, M. A.; Liu, B. D.; Zhang, X. L.; Yang, W. J.; Liu, L. S.; Jiang, X. | |
| Corresponding Author | Liu, B. D.(baodanliu@hotmail.com) ; Jiang, X.(xjiang@imr.ac.cn) |
| 2017 | |
| Source Publication | RSC ADVANCES
 |
| ISSN | 2046-2069 |
| Volume | 7Issue:5Pages:3012-3020 |
| Abstract | Neurological disorders have always triggered the interest of scientists due to the effects they have on the quality of life and the complexity they provide in their perception. Herein, we report a cellular-membrane inspired surface modification to fabricate a chemosensor for selective epinephrine detection. For this, well aligned ZnO nanorod arrays were grown on a silicon substrate using a feasible hydrothermal method and further utilized for the immobilization of a lipid membrane incorporated with calix[6]arene (in a 100 : 1 ratio) after modification with 1-octadecanthiol. Such surfaces were employed for selective epinephrine detection using electrochemical impedance spectroscopy as a transduction method. The detection process was based on the Lock & Key mechanism. A distinctive increase in charge transfer resistance was observed for epinephrine as compared to dopamine, leading to the conclusion that the sensor is sensitive and selective to epinephrine. This selectivity for epinephrine can be attributed to the slight differences in the molecular sizes of dopamine and epinephrine. Such electrochemical sensors can provide a very useful platform for the manufacturing of devices for monitoring the physiological concentrations of epinephrine. |
| Funding Organization | Knowledge Innovation Program of Institute of Metal Research (IMR), Chinese Academy of Science (CAS) ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; CAS President's International Fellowship for Postdoctoral Researchers |
| DOI | 10.1039/c6ra26250c |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Knowledge Innovation Program of Institute of Metal Research (IMR), Chinese Academy of Science (CAS)[Y2NCA111A1] ; Knowledge Innovation Program of Institute of Metal Research (IMR), Chinese Academy of Science (CAS)[Y3NCA111A1] ; Youth Innovation Promotion Association, Chinese Academy of Sciences[Y4NC711171] ; CAS President's International Fellowship for Postdoctoral Researchers[2015PM022] |
| WOS Research Area | Chemistry |
| WOS Subject | Chemistry, Multidisciplinary |
| WOS ID | WOS:000393748600072 |
| Publisher | ROYAL SOC CHEMISTRY |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/123721 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Liu, B. D.; Jiang, X. |
| Affiliation | Chinese Acad Sci, Shenyang Natl Lab Mat Sci SYNL, IMR, 72 Wenhua Rd, Shenyang 110016, Peoples R China |
| Recommended Citation GB/T 7714 | Mohsin, M. A.,Liu, B. D.,Zhang, X. L.,et al. Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine[J]. RSC ADVANCES,2017,7(5):3012-3020. |
| APA | Mohsin, M. A.,Liu, B. D.,Zhang, X. L.,Yang, W. J.,Liu, L. S.,&Jiang, X..(2017).Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine.RSC ADVANCES,7(5),3012-3020. |
| MLA | Mohsin, M. A.,et al."Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine".RSC ADVANCES 7.5(2017):3012-3020. |
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