IMR OpenIR
Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine
Mohsin, M. A.; Liu, B. D.; Zhang, X. L.; Yang, W. J.; Liu, L. S.; Jiang, X.
Corresponding AuthorLiu, B. D.(baodanliu@hotmail.com) ; Jiang, X.(xjiang@imr.ac.cn)
2017
Source PublicationRSC ADVANCES
ISSN2046-2069
Volume7Issue:5Pages:3012-3020
AbstractNeurological disorders have always triggered the interest of scientists due to the effects they have on the quality of life and the complexity they provide in their perception. Herein, we report a cellular-membrane inspired surface modification to fabricate a chemosensor for selective epinephrine detection. For this, well aligned ZnO nanorod arrays were grown on a silicon substrate using a feasible hydrothermal method and further utilized for the immobilization of a lipid membrane incorporated with calix[6]arene (in a 100 : 1 ratio) after modification with 1-octadecanthiol. Such surfaces were employed for selective epinephrine detection using electrochemical impedance spectroscopy as a transduction method. The detection process was based on the Lock & Key mechanism. A distinctive increase in charge transfer resistance was observed for epinephrine as compared to dopamine, leading to the conclusion that the sensor is sensitive and selective to epinephrine. This selectivity for epinephrine can be attributed to the slight differences in the molecular sizes of dopamine and epinephrine. Such electrochemical sensors can provide a very useful platform for the manufacturing of devices for monitoring the physiological concentrations of epinephrine.
Funding OrganizationKnowledge Innovation Program of Institute of Metal Research (IMR), Chinese Academy of Science (CAS) ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; CAS President's International Fellowship for Postdoctoral Researchers
DOI10.1039/c6ra26250c
Indexed BySCI
Language英语
Funding ProjectKnowledge Innovation Program of Institute of Metal Research (IMR), Chinese Academy of Science (CAS)[Y2NCA111A1] ; Knowledge Innovation Program of Institute of Metal Research (IMR), Chinese Academy of Science (CAS)[Y3NCA111A1] ; Youth Innovation Promotion Association, Chinese Academy of Sciences[Y4NC711171] ; CAS President's International Fellowship for Postdoctoral Researchers[2015PM022]
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000393748600072
PublisherROYAL SOC CHEMISTRY
Citation statistics
Cited Times:4[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/123725
Collection中国科学院金属研究所
Corresponding AuthorLiu, B. D.; Jiang, X.
AffiliationChinese Acad Sci, Shenyang Natl Lab Mat Sci SYNL, IMR, 72 Wenhua Rd, Shenyang 110016, Peoples R China
Recommended Citation
GB/T 7714
Mohsin, M. A.,Liu, B. D.,Zhang, X. L.,et al. Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine[J]. RSC ADVANCES,2017,7(5):3012-3020.
APA Mohsin, M. A.,Liu, B. D.,Zhang, X. L.,Yang, W. J.,Liu, L. S.,&Jiang, X..(2017).Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine.RSC ADVANCES,7(5),3012-3020.
MLA Mohsin, M. A.,et al."Cellular-membrane inspired surface modification of well aligned ZnO nanorods for chemosensing of epinephrine".RSC ADVANCES 7.5(2017):3012-3020.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Mohsin, M. A.]'s Articles
[Liu, B. D.]'s Articles
[Zhang, X. L.]'s Articles
Baidu academic
Similar articles in Baidu academic
[Mohsin, M. A.]'s Articles
[Liu, B. D.]'s Articles
[Zhang, X. L.]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Mohsin, M. A.]'s Articles
[Liu, B. D.]'s Articles
[Zhang, X. L.]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.