| Recent Advances on Biodegradable MgYREZr Magnesium Alloy | |
| Tan Lili1; Chen Junxiu1,2; Yu Xiaoming1; Yang Ke1 | |
| Corresponding Author | Tan Lili(lltan@imr.ac.cn) |
| 2017-10-11 | |
| Source Publication | ACTA METALLURGICA SINICA
 |
| ISSN | 0412-1961 |
| Volume | 53Issue:10Pages:1207-1214 |
| Abstract | In recent years, magnesium and its alloys as biodegradable materials have attracted much attention. Biodegradable MgYREZr, mainly WE43 alloy, with good integrated properties has been studied in favor. In this paper, the microstructure, mechanical properties, biodegradable property and biocompatibility of biodegradable MgYREZr alloy were reviewed, as well as the clinical results of the bone fixation screws developed in Germany using the alloy with similar composition to WE43. MgYREZr alloy presents uniform microstructure and higher mechanical properties after large plastic deformation with the grain size of less than 1 mm. The RE elements can be dissolved and stabilize the corrosion layer, which can decrease the degradation rate of the alloy accompanying with optimized heat treatment. The animal tests showed biocompatibility and good bioactivity. Clinical tests showed the MgYREZr alloy screws presented equivalent to titanium screws for the treatment of mild hallux valgus deformities, however resorption cysts was revealed by X-rays when the acute scaphoid fractures were treated with a double-threaded screw made of MgYREZr, and it was only after 6 months that the fractures were consolidated enough to allow physical work. So for different clinical cases, the degradation and biological behaviors of MgYREZr alloys need to be further studied in vitro and in vivo. To control the degradation rates to meet the different clinical requirements is still a major obstacle for biodegradable MgYREZr alloys to enlarge their clinical application. |
| Keyword | MgYREZr alloy microstructure mechanical property biodegradable property biocompatibility |
| Funding Organization | National Natural Science Foundation of China |
| DOI | 10.11900/0412.1961.2017.00266 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[81401773] ; National Natural Science Foundation of China[31500777] |
| WOS Research Area | Metallurgy & Metallurgical Engineering |
| WOS Subject | Metallurgy & Metallurgical Engineering |
| WOS ID | WOS:000416301400006 |
| Publisher | SCIENCE PRESS |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/125450 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Tan Lili |
| Affiliation | 1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Liaoning, Peoples R China |
| Recommended Citation GB/T 7714 | Tan Lili,Chen Junxiu,Yu Xiaoming,et al. Recent Advances on Biodegradable MgYREZr Magnesium Alloy[J]. ACTA METALLURGICA SINICA,2017,53(10):1207-1214. |
| APA | Tan Lili,Chen Junxiu,Yu Xiaoming,&Yang Ke.(2017).Recent Advances on Biodegradable MgYREZr Magnesium Alloy.ACTA METALLURGICA SINICA,53(10),1207-1214. |
| MLA | Tan Lili,et al."Recent Advances on Biodegradable MgYREZr Magnesium Alloy".ACTA METALLURGICA SINICA 53.10(2017):1207-1214. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment