Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing

doi:10.1016/j.msec.2018.08.013

IMR OpenIR

	Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing
	Yan, Xudong 1; Wan, Peng 2; Tan, Lili 1; Zhao, Mingchun 3; Qin, Ling 4; Yang, Ke 1
通讯作者	Wan, Peng(wanpeng@dgut.edu.cn)
	2018-12-01
发表期刊	MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
ISSN	0928-4931
卷号	93 页码:565-581
摘要	Mg-Cu alloys were designed by introducing the well-known antibacterial property of copper into magnesium alloy to solve the infection problem especially under the neutralised environment in vitro. In this paper, the Mg-Cu alloys with further processing by solution and extrusion were studied to optimise the corrosion-related performance for their future application. It was shown that the differences in the property profile of Mg-Cu alloys are dependent on different compositions as well as on different microstructures that are obtained by the different processing routes. Galvanic corrosion can be significantly relieved by solution treatment and extrusion due to decrease and well distribution of cathodic Mg2Cu phases. Negligible cytotoxicity were observed with rBMSCs incubation. Antibacterial assays proved that the alloys reduced the viability of Staphylococcus aureus by high alkalinity and copper ions releasing, especially in comparison with pure magnesium. Finally, the as-solutionized Mg-0.1Cu alloy showed the optimal corrosion properties and promising antibacterial activity, which warranted its potentials as antibacterial biodegradable implant materials.
关键词	Magnesium alloy Copper Corrosion Processing Antibacterial
资助者	National Natural Science Foundation of China ; National High Technology Research and Development Program of China (863 Program) ; Hong Kong Scholar Program ; CAS-Crouctier Founding Scheme for Joint Laboratories
DOI	10.1016/j.msec.2018.08.013
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[31500777] ; National Natural Science Foundation of China[51631009] ; National Natural Science Foundation of China[81501859] ; National High Technology Research and Development Program of China (863 Program)[2015AA033701] ; Hong Kong Scholar Program ; CAS-Crouctier Founding Scheme for Joint Laboratories[CAS14303]
WOS研究方向	Materials Science
WOS类目	Materials Science, Biomaterials
WOS记录号	WOS:000447569400054
出版者	ELSEVIER SCIENCE BV
引用统计	被引频次：72[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/130012
专题	中国科学院金属研究所
通讯作者	Wan, Peng
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Dongguan Univ Technol, Sch Mech Engn, Dongguan 523808, Peoples R China 3.Cent S Univ, Sch Mat Sci & Engn, Changsha 410083, Peoples R China 4.Chinese Univ Hong Kong, Li Ka Shing Inst Hlth Sci, Dept Orthopaed & Traumatol, Hong Kong, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Yan, Xudong,Wan, Peng,Tan, Lili,et al. Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2018,93:565-581.
APA	Yan, Xudong,Wan, Peng,Tan, Lili,Zhao, Mingchun,Qin, Ling,&Yang, Ke.(2018).Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,93,565-581.
MLA	Yan, Xudong,et al."Corrosion and biological performance of biodegradable magnesium alloys mediated by low copper addition and processing".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 93(2018):565-581.