IMR OpenIR
Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study
Peng, Wei1,2; Chen, Jun-Xiu3,4; Shan, Xian-Feng2; Wang, Yi-Chuan2; He, Fan2; Wang, Xue-Jin1; Tan, Li-Li3; Yang, Ke3
通讯作者Wang, Xue-Jin(wxj0411@aliyun.com) ; Tan, Li-Li(lltan@imr.ac.cn)
2019-06-01
发表期刊RARE METALS
ISSN1001-0521
卷号38期号:6页码:577-587
摘要A novel calcium-phosphate (Ca-P)-coated magnesium (Mg) membrane used for guided bone regeneration (GBR) was studied. The microstructural characterization, electrochemical test, immersion test, fluorescence labeling analysis and histopathological evaluation were carried out. The results showed that Ca-P coating could obviously improve the corrosion resistance of the pure Mg membrane. The in vivo results showed that Mg membrane coated with Ca-P would take 8weeks to be completely absorbed. However, Mg membrane was completely absorbed within 1week. Histopathological evaluation showed that the Ca-P-coated Mg membranes were significantly better than Ti membranes at the early implantation time (4weeks), and with the time prolonging, the performance of the coated Mg membrane was not as good as pure Ti membranes (but still better than blank group) at 8 and 12weeks. The coated biodegradable Mg membrane had a good promising application in GBR. But further studies have to be done to further decrease the degradation rate of pure Mg membrane.
关键词Bone defect Guided bone regeneration Ca-P-coated magnesium (Mg) membrane Bioabsorbable membrane
资助者Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement ; Shenyang Key R&D and Technology Transfer Program
DOI10.1007/s12598-019-01273-8
收录类别SCI
语种英语
资助项目Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1101804] ; Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1100604] ; Shenyang Key R&D and Technology Transfer Program[Z18-0-027]
WOS研究方向Materials Science ; Metallurgy & Metallurgical Engineering
WOS类目Materials Science, Multidisciplinary ; Metallurgy & Metallurgical Engineering
WOS记录号WOS:000469800600012
出版者NONFERROUS METALS SOC CHINA
引用统计
被引频次:23[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.imr.ac.cn/handle/321006/133812
专题中国科学院金属研究所
通讯作者Wang, Xue-Jin; Tan, Li-Li
作者单位1.Dalian Univ, Dept Stomatol, Zhongshan Hosp, Dalian 116001, Peoples R China
2.Dalian Univ, Sch Med, Dalian 116622, Peoples R China
3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China
4.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Liaoning, Peoples R China
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GB/T 7714
Peng, Wei,Chen, Jun-Xiu,Shan, Xian-Feng,et al. Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study[J]. RARE METALS,2019,38(6):577-587.
APA Peng, Wei.,Chen, Jun-Xiu.,Shan, Xian-Feng.,Wang, Yi-Chuan.,He, Fan.,...&Yang, Ke.(2019).Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study.RARE METALS,38(6),577-587.
MLA Peng, Wei,et al."Mg-based absorbable membrane for guided bone regeneration (GBR): a pilot study".RARE METALS 38.6(2019):577-587.
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