In vitro degradation and antibacterial property of a copper-containing micro-arc oxidation coating on Mg-2Zn-1Gd-0.5Zr alloy

doi:10.1016/j.colsurfb.2019.03.023

IMR OpenIR

	In vitro degradation and antibacterial property of a copper-containing micro-arc oxidation coating on Mg-2Zn-1Gd-0.5Zr alloy
	Chen, Junxiu 1,2; Zhang, Yi 1,2; Ibrahim, Muhammad 1,2; Etim, Iniobong P.1,2; Tan, Lili 1; Yang, Ke 1
通讯作者	Tan, Lili(lltan@imr.ac.cn) ; Yang, Ke(kyang@imr.ac.cn)
	2019-07-01
发表期刊	COLLOIDS AND SURFACES B-BIOINTERFACES
ISSN	0927-7765
卷号	179 页码:77-86
摘要	Copper (Cu) has a good antibacterial effect and micro-arc oxidation (MAO) coating has good corrosion resistance for magnesium (Mg) alloys. If they are combined together, the coated Mg alloy is expected to have both good corrosion resistance and antibacterial effect. In this work, the degradation, antibacterial property and cytotoxicity of a Cu-containing MAO coating on an extruded Mg-2Zn-1Gd-0.5Zr alloy were systematically studied. The results revealed that the addition of Cu could further improve the degradation resistance of MAO coated alloy. After two weeks immersion, the corrosion rate of Cu + MAO coated alloy was 0.16 mm/y, lower than those of both MAO coated and uncoated alloy. The release of Cu2+ from Cu + MAO coated alloy inhibited the bacterial proliferation. After 12 h co-culture, the antibacterial rate reached 96%. Cytotoxicity test (MG63 cell) showed that Cu + MAO coated alloy had good biocompatibility. The Cu + MAO coating has great potential for application on Mg alloys due to its good corrosion resistance, antibacterial property and good biocompatibility.
关键词	Copper MAO coating Corrosion resistance Antibacterial property Cytotoxicity
资助者	Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement ; Natural Science Foundation of China ; Shenyang Key R&D and Technology Transfer Program
DOI	10.1016/j.colsurfb.2019.03.023
收录类别	SCI
语种	英语
资助项目	Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1101804] ; Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1100604] ; Natural Science Foundation of China[51631009] ; Shenyang Key R&D and Technology Transfer Program[Z18-0-027]
WOS研究方向	Biophysics ; Chemistry ; Materials Science
WOS类目	Biophysics ; Chemistry, Physical ; Materials Science, Biomaterials
WOS记录号	WOS:000471736600009
出版者	ELSEVIER SCIENCE BV
引用统计	被引频次：74[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/134197
专题	中国科学院金属研究所
通讯作者	Tan, Lili; Yang, Ke
作者单位	1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang 110016, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Chen, Junxiu,Zhang, Yi,Ibrahim, Muhammad,et al. In vitro degradation and antibacterial property of a copper-containing micro-arc oxidation coating on Mg-2Zn-1Gd-0.5Zr alloy[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2019,179:77-86.
APA	Chen, Junxiu,Zhang, Yi,Ibrahim, Muhammad,Etim, Iniobong P.,Tan, Lili,&Yang, Ke.(2019).In vitro degradation and antibacterial property of a copper-containing micro-arc oxidation coating on Mg-2Zn-1Gd-0.5Zr alloy.COLLOIDS AND SURFACES B-BIOINTERFACES,179,77-86.
MLA	Chen, Junxiu,et al."In vitro degradation and antibacterial property of a copper-containing micro-arc oxidation coating on Mg-2Zn-1Gd-0.5Zr alloy".COLLOIDS AND SURFACES B-BIOINTERFACES 179(2019):77-86.