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Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material
Ma, Zheng1; Gao, Ming1,4; Na, Di2; Li, Yangde3; Tan, Lili1; Yang, Ke1
Corresponding AuthorTan, Lili(lltan@imr.ac.cn) ; Yang, Ke(kyang@imr.ac.cn)
2019-10-01
Source PublicationMATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
ISSN0928-4931
Volume103Pages:8
AbstractBiodegradable Fe based alloys have been investigated for fracture fixation and cardiovascular support to overcome complications of permanent implants. This study was focused on the development of a new Fe-Mn-CCu alloy with antibacterial and anti-encrustation properties as a urinary implant material. The microstructure and mechanical properties of the alloy were studied. The degradation behavior, antibacterial and anti-encrustation properties were evaluated by immersion test, antibacterial test and encrustation test, respectively. The results showed that Fe-Mn-C-Cu alloy was a non-magnetic, biodegradable, anti-bacterial and anti-encrustation alloy that could inhibit the biofilm and stone formations on its surface through the dual effects of degradation and Cu ions release. The study revealed the preliminary mechanisms of anti-infection and anti-encrustation for Fe-Mn-C-Cu alloy due to the continuous release of Cu2+ ions, which provides a new idea for application of biodegradable Fe-based material and the treatment of urinary tract infections and stones in the urinary system.
KeywordFe-Mn-C-Cu alloy Biodegradable Anti-infection Urinary implant material Anti-encrustation
Funding OrganizationKey Program of China on Biomedical Materials Research and Tissue and Organ Replacement ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project
DOI10.1016/j.msec.2019.05.003
Indexed BySCI
Language英语
Funding ProjectKey Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1101804] ; Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1100604] ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project[Z18-0-027]
WOS Research AreaMaterials Science
WOS SubjectMaterials Science, Biomaterials
WOS IDWOS:000480664900021
PublisherELSEVIER
Citation statistics
Cited Times:7[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/134996
Collection中国科学院金属研究所
Corresponding AuthorTan, Lili; Yang, Ke
Affiliation1.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China
2.China Med Univ, Dept Surg Oncol, Affiliated Hosp 1, Beijing, Peoples R China
3.Dongguan Eontech Co Ltd, Dongguan 523662, Peoples R China
4.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang, Liaoning, Peoples R China
Recommended Citation
GB/T 7714
Ma, Zheng,Gao, Ming,Na, Di,et al. Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2019,103:8.
APA Ma, Zheng,Gao, Ming,Na, Di,Li, Yangde,Tan, Lili,&Yang, Ke.(2019).Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,103,8.
MLA Ma, Zheng,et al."Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 103(2019):8.
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