| Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material | |
| Ma, Zheng1; Gao, Ming1,4; Na, Di2; Li, Yangde3; Tan, Lili1; Yang, Ke1 | |
| Corresponding Author | Tan, Lili(lltan@imr.ac.cn) ; Yang, Ke(kyang@imr.ac.cn) |
| 2019-10-01 | |
| Source Publication | MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
 |
| ISSN | 0928-4931 |
| Volume | 103Pages:8 |
| Abstract | Biodegradable Fe based alloys have been investigated for fracture fixation and cardiovascular support to overcome complications of permanent implants. This study was focused on the development of a new Fe-Mn-CCu alloy with antibacterial and anti-encrustation properties as a urinary implant material. The microstructure and mechanical properties of the alloy were studied. The degradation behavior, antibacterial and anti-encrustation properties were evaluated by immersion test, antibacterial test and encrustation test, respectively. The results showed that Fe-Mn-C-Cu alloy was a non-magnetic, biodegradable, anti-bacterial and anti-encrustation alloy that could inhibit the biofilm and stone formations on its surface through the dual effects of degradation and Cu ions release. The study revealed the preliminary mechanisms of anti-infection and anti-encrustation for Fe-Mn-C-Cu alloy due to the continuous release of Cu2+ ions, which provides a new idea for application of biodegradable Fe-based material and the treatment of urinary tract infections and stones in the urinary system. |
| Keyword | Fe-Mn-C-Cu alloy Biodegradable Anti-infection Urinary implant material Anti-encrustation |
| Funding Organization | Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project |
| DOI | 10.1016/j.msec.2019.05.003 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1101804] ; Key Program of China on Biomedical Materials Research and Tissue and Organ Replacement[2016YFC1100604] ; Double Hundred Project Plan of Shenyang Key Scientific and Technological Achievements Transformation Project[Z18-0-027] |
| WOS Research Area | Materials Science |
| WOS Subject | Materials Science, Biomaterials |
| WOS ID | WOS:000480664900021 |
| Publisher | ELSEVIER |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/134996 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Tan, Lili; Yang, Ke |
| Affiliation | 1.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China 2.China Med Univ, Dept Surg Oncol, Affiliated Hosp 1, Beijing, Peoples R China 3.Dongguan Eontech Co Ltd, Dongguan 523662, Peoples R China 4.Univ Sci & Technol China, Sch Mat Sci & Engn, Shenyang, Liaoning, Peoples R China |
| Recommended Citation GB/T 7714 | Ma, Zheng,Gao, Ming,Na, Di,et al. Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material[J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,2019,103:8. |
| APA | Ma, Zheng,Gao, Ming,Na, Di,Li, Yangde,Tan, Lili,&Yang, Ke.(2019).Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material.MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS,103,8. |
| MLA | Ma, Zheng,et al."Study on a biodegradable antibacterial Fe-Mn-C-Cu alloy as urinary implant material".MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS 103(2019):8. |
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