Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys

doi:10.1021/acsomega.9b02041

IMR OpenIR

	Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys
	Wu, Weiwei 1; Yu, Xiaoming 3; Zhao, Yan 2; Jiang, Xiran 1; Yang, Huazhe 1
通讯作者	Yang, Huazhe(hzyang@cmu.edu.cn)
	2019-09-17
发表期刊	ACS OMEGA
ISSN	2470-1343
卷号	4 期号:12 页码:15139-15148
摘要	Biodegradable Mg alloys have good bioactivity and suitable mechanical properties, which is desirable for application in the clinical fields. However, the biocompatibility of Mg alloys during the degradation process has always been a concern. In this paper, the corrosion behavior of AZ91 alloys in a simulated cell culture environment was studied, especially the insoluble corrosion product during the degradation was characterized, and the biocompatibility of the insoluble corrosion products was evaluated. The results of immersion test showed that the corrosion rate of the AZ91 alloy was low under the condition of high CO2 and humidity, especially in phosphate-buffered saline. Moreover, the insoluble corrosion product was MgCO3 center dot 3H(2)O, which showed a needle-like, circular aggregated, and square-radial feature. Meanwhile, MgCO3 center dot 3H(2)O showed poor cell biocompatibility by increasing the pH and Mg2+ content of the culture solution, which may affect the biocompatibility of Mg alloys.
资助者	National Natural Science Foundation of China
DOI	10.1021/acsomega.9b02041
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[81803461] ; National Natural Science Foundation of China[81500897]
WOS研究方向	Chemistry
WOS类目	Chemistry, Multidisciplinary
WOS记录号	WOS:000488838700054
出版者	AMER CHEMICAL SOC
引用统计	被引频次：14[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/135812
专题	中国科学院金属研究所
通讯作者	Yang, Huazhe
作者单位	1.China Med Univ, Sch Fundamental Sci, Shenyang 110122, Liaoning, Peoples R China 2.China Med Univ, Sch Pharm, Shenyang 110122, Liaoning, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China
推荐引用方式 GB/T 7714	Wu, Weiwei,Yu, Xiaoming,Zhao, Yan,et al. Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys[J]. ACS OMEGA,2019,4(12):15139-15148.
APA	Wu, Weiwei,Yu, Xiaoming,Zhao, Yan,Jiang, Xiran,&Yang, Huazhe.(2019).Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys.ACS OMEGA,4(12),15139-15148.
MLA	Wu, Weiwei,et al."Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys".ACS OMEGA 4.12(2019):15139-15148.