| Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys | |
| Wu, Weiwei1; Yu, Xiaoming3; Zhao, Yan2; Jiang, Xiran1; Yang, Huazhe1 | |
| Corresponding Author | Yang, Huazhe(hzyang@cmu.edu.cn) |
| 2019-09-17 | |
| Source Publication | ACS OMEGA
 |
| ISSN | 2470-1343 |
| Volume | 4Issue:12Pages:15139-15148 |
| Abstract | Biodegradable Mg alloys have good bioactivity and suitable mechanical properties, which is desirable for application in the clinical fields. However, the biocompatibility of Mg alloys during the degradation process has always been a concern. In this paper, the corrosion behavior of AZ91 alloys in a simulated cell culture environment was studied, especially the insoluble corrosion product during the degradation was characterized, and the biocompatibility of the insoluble corrosion products was evaluated. The results of immersion test showed that the corrosion rate of the AZ91 alloy was low under the condition of high CO2 and humidity, especially in phosphate-buffered saline. Moreover, the insoluble corrosion product was MgCO3 center dot 3H(2)O, which showed a needle-like, circular aggregated, and square-radial feature. Meanwhile, MgCO3 center dot 3H(2)O showed poor cell biocompatibility by increasing the pH and Mg2+ content of the culture solution, which may affect the biocompatibility of Mg alloys. |
| Funding Organization | National Natural Science Foundation of China |
| DOI | 10.1021/acsomega.9b02041 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[81803461] ; National Natural Science Foundation of China[81500897] |
| WOS Research Area | Chemistry |
| WOS Subject | Chemistry, Multidisciplinary |
| WOS ID | WOS:000488838700054 |
| Publisher | AMER CHEMICAL SOC |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/135812 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Yang, Huazhe |
| Affiliation | 1.China Med Univ, Sch Fundamental Sci, Shenyang 110122, Liaoning, Peoples R China 2.China Med Univ, Sch Pharm, Shenyang 110122, Liaoning, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Liaoning, Peoples R China |
| Recommended Citation GB/T 7714 | Wu, Weiwei,Yu, Xiaoming,Zhao, Yan,et al. Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys[J]. ACS OMEGA,2019,4(12):15139-15148. |
| APA | Wu, Weiwei,Yu, Xiaoming,Zhao, Yan,Jiang, Xiran,&Yang, Huazhe.(2019).Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys.ACS OMEGA,4(12),15139-15148. |
| MLA | Wu, Weiwei,et al."Characterization and Biocompatibility of Insoluble Corrosion Products of AZ91 Mg Alloys".ACS OMEGA 4.12(2019):15139-15148. |
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