| Effect of copper-doped titanium nitride coating on angiogenesis | |
| Liu, Hui1,2; Zhang, Xiyue1,2; Jin, Shujing3; Zhao, Yanhui1; Ren, Ling1; Yang, Ke1 | |
| Corresponding Author | Zhao, Yanhui(yhzhao@imr.ac.cn) ; Ren, Ling(lren@imr.ac.cn) |
| 2020-06-15 | |
| Source Publication | MATERIALS LETTERS
 |
| ISSN | 0167-577X |
| Volume | 269Pages:4 |
| Abstract | This work studied the in vitro angiogenic response of human umbilical vein endothelial cells on the copper-doped titanium nitride (TiCuN) coating, which has been proved to own good antibacterial ability and excellent corrosion resistance as well as wear resistance. It was found that TiCuN coating had no cytotoxic effect and promoted the early cell proliferation, furthermore it significantly promoted the mRNA expressions of eNOS and VEGF, also obviously enhanced the cell migration and tube formation compared with TiN coating, which indicated that TiCuN coating can improve the angiogenesis ability of biomaterials and would gain new opportunities for the applications in orthopedic and cardiovascular fields. (C) 2020 Elsevier B.V. All rights reserved. |
| Keyword | Biomaterials Coating Angiogenesis Human umbilical vein endothelial cells |
| Funding Organization | National Key Research and Development Program of China ; LiaoNing Revitalization Talents Program ; National Natural Science Foundation ; Key Projects for Foreign Cooperation of Bureau of International Cooperation Chinese Academy of Sciences |
| DOI | 10.1016/j.matlet.2020.127634 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Key Research and Development Program of China[2018YFC1106601] ; National Key Research and Development Program of China[2016YFC1100601] ; LiaoNing Revitalization Talents Program[XLYC1807069] ; National Natural Science Foundation[51631009] ; National Natural Science Foundation[31870954] ; Key Projects for Foreign Cooperation of Bureau of International Cooperation Chinese Academy of Sciences[174321KYSB2018000] |
| WOS Research Area | Materials Science ; Physics |
| WOS Subject | Materials Science, Multidisciplinary ; Physics, Applied |
| WOS ID | WOS:000523600100014 |
| Publisher | ELSEVIER |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/138036 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Zhao, Yanhui; Ren, Ling |
| Affiliation | 1.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China 2.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei 230026, Peoples R China 3.Nanjing Iron & Steel Co, Res Inst, Nanjing 210035, Peoples R China |
| Recommended Citation GB/T 7714 | Liu, Hui,Zhang, Xiyue,Jin, Shujing,et al. Effect of copper-doped titanium nitride coating on angiogenesis[J]. MATERIALS LETTERS,2020,269:4. |
| APA | Liu, Hui,Zhang, Xiyue,Jin, Shujing,Zhao, Yanhui,Ren, Ling,&Yang, Ke.(2020).Effect of copper-doped titanium nitride coating on angiogenesis.MATERIALS LETTERS,269,4. |
| MLA | Liu, Hui,et al."Effect of copper-doped titanium nitride coating on angiogenesis".MATERIALS LETTERS 269(2020):4. |
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