| A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg | |
| Li, Junlei1; Xu, Wenwu1; Lin, Xiao2; Cao, Fang1; Yang, Jiahui1; Li, Lu1; Wei, Xiaowei1; Zhang, Xiuzhi1; Zhao, Dewei1; Yang, Ke3 | |
| Corresponding Author | Zhao, Dewei(zhaodewei2016@163.com) |
| 2020-06-01 | |
| Source Publication | COLLOIDS AND SURFACES B-BIOINTERFACES
 |
| ISSN | 0927-7765 |
| Volume | 190Pages:10 |
| Abstract | Enhanced corrosion resistance and accelerated new bone formation are desired to make Mg and its alloys to be ideal candidate for bone biomaterial. For this purpose, a CDHA/MgF2 bi-layer coating was prepared on high purity Mg by a combination of fluoride treatment and hydrothermal treatment. The coating exhibited a nanoscale surface topography. Enhanced adhesion strength and corrosion resistance was obtained for the CDHA/MgF2 bi-layer coating. In vitro cell experiment showed that the adhesion, proliferation and differentiation of MG63 cells were significantly improved on Mg with CDHA/MgF2 coating compared to that on Mg with HA coating and MgF2 coating. In conclusion, this study provides a promising surface modification method for Mg metal with enhanced corrosion resistance and superior osteogenic bioactivity. |
| Keyword | Biodegradable Mg CDHA/MgF(2)bi-layer coating Nanorod-like morphology Corrosion resistance Osteogenic capability |
| Funding Organization | National Key R&D Program of China ; National Natural Science Foundation of China ; Doctor Initial Foundation of Liaoning Province ; Affiliated Zhongshan Hospital of Dalian University |
| DOI | 10.1016/j.colsurfb.2020.110911 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Key R&D Program of China[2016YFC1102000] ; National Natural Science Foundation of China[81672139] ; National Natural Science Foundation of China[81702129] ; Doctor Initial Foundation of Liaoning Province[20170520017] ; Affiliated Zhongshan Hospital of Dalian University[DLDXZSYYDK201701] |
| WOS Research Area | Biophysics ; Chemistry ; Materials Science |
| WOS Subject | Biophysics ; Chemistry, Physical ; Materials Science, Biomaterials |
| WOS ID | WOS:000530677200027 |
| Publisher | ELSEVIER |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/138732 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Zhao, Dewei |
| Affiliation | 1.Dalian Univ, Dept Orthopaed, Affiliated Zhongshan Hosp, Dalian 116001, Peoples R China 2.Soochow Univ, Med Coll, Orthopaed Inst, Suzhou 215006, Jiangsu, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China |
| Recommended Citation GB/T 7714 | Li, Junlei,Xu, Wenwu,Lin, Xiao,et al. A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg[J]. COLLOIDS AND SURFACES B-BIOINTERFACES,2020,190:10. |
| APA | Li, Junlei.,Xu, Wenwu.,Lin, Xiao.,Cao, Fang.,Yang, Jiahui.,...&Yang, Ke.(2020).A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg.COLLOIDS AND SURFACES B-BIOINTERFACES,190,10. |
| MLA | Li, Junlei,et al."A Ca-deficientca-deficient hydroxyapatite (CDHA)/MgF2 bi-layer coating with unique nano-scale topography on biodegradable high-purity Mg".COLLOIDS AND SURFACES B-BIOINTERFACES 190(2020):10. |
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