| Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer | |
| Meng, Yingying1,2; Zhang, Dan1,2; Jia, Xingya1,2; Xiao, Keshen3; Lin, Xiao4,5; Yang, Yi6; Xu, Dake6; Wang, Qiang1,2 | |
| Corresponding Author | Jia, Xingya(jiaxingya_cmu@163.com) ; Lin, Xiao(xlin@suda.edu.cn) ; Wang, Qiang(mfqwang@163.com) |
| 2020-06-06 | |
| Source Publication | MEDICAL SCIENCE MONITOR
 |
| ISSN | 1643-3750 |
| Volume | 26Pages:10 |
| Abstract | Background: The goal of the present work was to assess the antibacterial activity of nano-magnesium hydroxide (NMH) against Streptococcus mutans (S. mutans) and to explore the antimicrobial function of AH Plus (TM) sealer incorporating NMH. Material/Methods: The antimicrobial behavior of NMH against S. mutans was evaluated with bactericidal tests. A modified direct contact test was used to assess the antimicrobial activity of unset AH Plus containing NMH after 5 minutes, 20 minutes, and 60 minutes of contact with bacteria. The antimicrobial effects and the amount of surface-adhering bacteria of the solidified materials were explored by SEM and confocal laser scanning microscopy, respectively. Results: NMH powder presented excellent antimicrobial activity against S. mutans. Mg-2* and OH- were not the main fac- tors resulting in bacterial death. Approximately 93.1% and 98% of the S. mutans were killed in the AH Plus+7% NMH group after incubation for 5 minutes and 20 minutes, respectively. AH Plus with 5% or 7% NMH were more potent against S. mutans compared with AH Plus alone (P<0.05). Moreover, the antibacterial function of AH Plus was lost after setting. NMH enabled the solidified AH Plus to still have antibacterial properties on the seventh day. Conclusions: NMH can be used to modify AH Plus sealer to eradicate residual bacteria and prevent reinfection. |
| Keyword | Magnesium Hydroxide Root Canal Therapy Streptococcus mutans |
| DOI | 10.12659/MSM.922920 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Research & Experimental Medicine |
| WOS Subject | Medicine, Research & Experimental |
| WOS ID | WOS:000538389900001 |
| Publisher | INT SCIENTIFIC INFORMATION, INC |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/139154 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Jia, Xingya; Lin, Xiao; Wang, Qiang |
| Affiliation | 1.China Med Univ, Sch & Hosp Stomatol, Shenyang, Liaoning, Peoples R China 2.Liaoning Prov Key Lab Oral Dis, Shenyang, Liaoning, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China 4.Soochow Univ, Affiliated Hosp 1, Orthopaed Inst, Suzhou, Jiangsu, Peoples R China 5.Soochow Univ, Affiliated Hosp 1, Dept Orthopaed, Suzhou, Jiangsu, Peoples R China 6.Northeastern Univ, Key Lab Anisotropy & Texture Mat, Shenyang, Liaoning, Peoples R China |
| Recommended Citation GB/T 7714 | Meng, Yingying,Zhang, Dan,Jia, Xingya,et al. Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer[J]. MEDICAL SCIENCE MONITOR,2020,26:10. |
| APA | Meng, Yingying.,Zhang, Dan.,Jia, Xingya.,Xiao, Keshen.,Lin, Xiao.,...&Wang, Qiang.(2020).Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer.MEDICAL SCIENCE MONITOR,26,10. |
| MLA | Meng, Yingying,et al."Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer".MEDICAL SCIENCE MONITOR 26(2020):10. |
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