IMR OpenIR
Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer
Meng, Yingying1,2; Zhang, Dan1,2; Jia, Xingya1,2; Xiao, Keshen3; Lin, Xiao4,5; Yang, Yi6; Xu, Dake6; Wang, Qiang1,2
Corresponding AuthorJia, Xingya(jiaxingya_cmu@163.com) ; Lin, Xiao(xlin@suda.edu.cn) ; Wang, Qiang(mfqwang@163.com)
2020-06-06
Source PublicationMEDICAL SCIENCE MONITOR
ISSN1643-3750
Volume26Pages:10
AbstractBackground: The goal of the present work was to assess the antibacterial activity of nano-magnesium hydroxide (NMH) against Streptococcus mutans (S. mutans) and to explore the antimicrobial function of AH Plus (TM) sealer incorporating NMH. Material/Methods: The antimicrobial behavior of NMH against S. mutans was evaluated with bactericidal tests. A modified direct contact test was used to assess the antimicrobial activity of unset AH Plus containing NMH after 5 minutes, 20 minutes, and 60 minutes of contact with bacteria. The antimicrobial effects and the amount of surface-adhering bacteria of the solidified materials were explored by SEM and confocal laser scanning microscopy, respectively. Results: NMH powder presented excellent antimicrobial activity against S. mutans. Mg-2* and OH- were not the main fac- tors resulting in bacterial death. Approximately 93.1% and 98% of the S. mutans were killed in the AH Plus+7% NMH group after incubation for 5 minutes and 20 minutes, respectively. AH Plus with 5% or 7% NMH were more potent against S. mutans compared with AH Plus alone (P<0.05). Moreover, the antibacterial function of AH Plus was lost after setting. NMH enabled the solidified AH Plus to still have antibacterial properties on the seventh day. Conclusions: NMH can be used to modify AH Plus sealer to eradicate residual bacteria and prevent reinfection.
KeywordMagnesium Hydroxide Root Canal Therapy Streptococcus mutans
DOI10.12659/MSM.922920
Indexed BySCI
Language英语
WOS Research AreaResearch & Experimental Medicine
WOS SubjectMedicine, Research & Experimental
WOS IDWOS:000538389900001
PublisherINT SCIENTIFIC INFORMATION, INC
Citation statistics
Document Type期刊论文
Identifierhttp://ir.imr.ac.cn/handle/321006/139157
Collection中国科学院金属研究所
Corresponding AuthorJia, Xingya; Lin, Xiao; Wang, Qiang
Affiliation1.China Med Univ, Sch & Hosp Stomatol, Shenyang, Liaoning, Peoples R China
2.Liaoning Prov Key Lab Oral Dis, Shenyang, Liaoning, Peoples R China
3.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China
4.Soochow Univ, Affiliated Hosp 1, Orthopaed Inst, Suzhou, Jiangsu, Peoples R China
5.Soochow Univ, Affiliated Hosp 1, Dept Orthopaed, Suzhou, Jiangsu, Peoples R China
6.Northeastern Univ, Key Lab Anisotropy & Texture Mat, Shenyang, Liaoning, Peoples R China
Recommended Citation
GB/T 7714
Meng, Yingying,Zhang, Dan,Jia, Xingya,et al. Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer[J]. MEDICAL SCIENCE MONITOR,2020,26:10.
APA Meng, Yingying.,Zhang, Dan.,Jia, Xingya.,Xiao, Keshen.,Lin, Xiao.,...&Wang, Qiang.(2020).Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer.MEDICAL SCIENCE MONITOR,26,10.
MLA Meng, Yingying,et al."Antimicrobial Activity of Nano-Magnesium Hydroxide Against Oral Bacteria and Application in Root Canal Sealer".MEDICAL SCIENCE MONITOR 26(2020):10.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Meng, Yingying]'s Articles
[Zhang, Dan]'s Articles
[Jia, Xingya]'s Articles
Baidu academic
Similar articles in Baidu academic
[Meng, Yingying]'s Articles
[Zhang, Dan]'s Articles
[Jia, Xingya]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Meng, Yingying]'s Articles
[Zhang, Dan]'s Articles
[Jia, Xingya]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.