| Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro | |
| Luo, Xue1; Liang, Chen2; Li, Ning3; Zhu, Yuhe1; Cao, Nanjue4; Wang, Jin1; Liu, Keda1; Zhao, Hongwei3; Wang, Zhenbo2; Wang, Wei1 | |
| Corresponding Author | Zhao, Hongwei(13931386052@163.com) ; Wang, Zhenbo(zbwang@imr.ac.cn) ; Wang, Wei(wwang75@cmu.edu.cn) |
| 2020-06-05 | |
| Source Publication | JOURNAL OF NANOMATERIALS
 |
| ISSN | 1687-4110 |
| Volume | 2020Pages:11 |
| Abstract | Titanium (Ti) is widely used in oral implants. However, there is still a challenge to promote the osseointegration of bone tissue on the surface of Ti. To solve this problem, we prepared novel gradient nanostructured (GNS) Ti and studied the effect of GNS on the adhesion, proliferation, and apoptosis of MG63 cellsin vitro. The results demonstrated that the GNS Ti promoted the adhesion effect and proliferation of MG63 cells better than the annealed Ti, while the ability of GNS Ti to inhibit cell apoptosis was better than that of the annealed Ti, the preliminary mechanism of which indicated by this study might be the enhanced mineralization capacity, protein adsorption ability, and hydrophilicity of the GNS Ti due to its specific nanostructure which improved the cell behaviours. The results in this study provide the theoretical and experimental foundations for the applications of GNS Ti in dental implants and joint replacements. |
| Funding Organization | National Natural Science Foundation of China ; Liaoning Provincial Key Research Plan Guidance Project ; Liaoning Provincial Natural Science Foundation Guidance Project ; Liaoning Province, Colleges and Universities Basic Research Project ; Central Government of Liaoning Province to Guide Local Science and Technology Development Project ; Shenyang Major Scientific and Technological Innovation Research and Development Plan ; Second Batch of Medical Education Scientific Research Projects of the 13th Five-Year Plan of China Medical University |
| DOI | 10.1155/2020/9480537 |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Natural Science Foundation of China[81970980] ; Liaoning Provincial Key Research Plan Guidance Project[2018225078] ; Liaoning Provincial Natural Science Foundation Guidance Project[2019-ZD-0749] ; Liaoning Province, Colleges and Universities Basic Research Project[LFWK201717] ; Central Government of Liaoning Province to Guide Local Science and Technology Development Project[2017108001] ; Shenyang Major Scientific and Technological Innovation Research and Development Plan[19-112-4-027] ; Second Batch of Medical Education Scientific Research Projects of the 13th Five-Year Plan of China Medical University[YDJK2018017] |
| WOS Research Area | Science & Technology - Other Topics ; Materials Science |
| WOS Subject | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| WOS ID | WOS:000548802600001 |
| Publisher | HINDAWI LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/139824 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Zhao, Hongwei; Wang, Zhenbo; Wang, Wei |
| Affiliation | 1.China Med Univ, Sch & Hosp Stomatol, Liaoning Prov Key Lab Oral Dis, Shenyang 110001, Peoples R China 2.Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Inst Met Res, Shenyang 110016, Peoples R China 3.Fourth Cent Hosp Baoding City, Dept Orthoped, Baoding 072350, Peoples R China 4.Zhejiang Univ, Affiliated Hosp 4, Sch Med, Yiwu 322000, Peoples R China |
| Recommended Citation GB/T 7714 | Luo, Xue,Liang, Chen,Li, Ning,et al. Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro[J]. JOURNAL OF NANOMATERIALS,2020,2020:11. |
| APA | Luo, Xue.,Liang, Chen.,Li, Ning.,Zhu, Yuhe.,Cao, Nanjue.,...&Wang, Wei.(2020).Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro.JOURNAL OF NANOMATERIALS,2020,11. |
| MLA | Luo, Xue,et al."Effect of Gradient Nanostructured Ti on Behaviours of MG63 Cells In Vitro".JOURNAL OF NANOMATERIALS 2020(2020):11. |
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