| Decellularized Extracellular Matrices for Tissue Engineering and Regeneration | |
| Ge, Fang1,2; Lu, Yuhe1,3; Li, Qian1,2; Zhang, Xing1,4 | |
| Corresponding Author | Zhang, Xing(xingzhang@imr.ac.cn) |
| 2020 | |
| Source Publication | BIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE
 |
| ISSN | 0065-2598 |
| Volume | 1250Pages:15-31 |
| Abstract | Decellularized extracellular matrices (dECMs) from mammalian tissues and organs are particularly interesting as scaffolds for tissue engineering and regeneration when considering their ability to retain chemical compositions and three-dimensional (3D) microstructures that are similar to native ECMs. This review discusses the advantages and disadvantages of different decellularization methods that use various agents, such as ionic and nonionic detergents and biological enzymes. The applications of dECMs as scaffolds or hydrogels for tissue engineering of specific tissues including heart valves, blood vessels, and skin, as well as their performance in vitro and in vivo, are also discussed. In addition, whole organ regeneration (i.e., the heart, kidney, liver) using dECM scaffolds has been explored, which are able to recapitulate partial functions of native organs. |
| Keyword | Decellularization Recellularization Extracellular matrices Microstructure Tissue engineering Organ regeneration |
| DOI | 10.1007/978-981-15-3262-7_2 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Cell Biology ; Materials Science |
| WOS Subject | Cell & Tissue Engineering ; Materials Science, Biomaterials |
| WOS ID | WOS:000556133600003 |
| Publisher | SPRINGER-VERLAG SINGAPORE PTE LTD |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/140143 |
| Collection | 中国科学院金属研究所 |
| Corresponding Author | Zhang, Xing |
| Affiliation | 1.Chinese Acad Sci, Inst Met Res, Shenyang, Liaoning, Peoples R China 2.Northeastern Univ, Dept Chem, Shenyang, Liaoning, Peoples R China 3.Northeastern Univ, Sch Mat Sci & Engn, Shenyang, Liaoning, Peoples R China 4.Univ Sci & Technol China, Sch Mat Sci & Engn, Hefei, Anhui, Peoples R China |
| Recommended Citation GB/T 7714 | Ge, Fang,Lu, Yuhe,Li, Qian,et al. Decellularized Extracellular Matrices for Tissue Engineering and Regeneration[J]. BIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE,2020,1250:15-31. |
| APA | Ge, Fang,Lu, Yuhe,Li, Qian,&Zhang, Xing.(2020).Decellularized Extracellular Matrices for Tissue Engineering and Regeneration.BIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE,1250,15-31. |
| MLA | Ge, Fang,et al."Decellularized Extracellular Matrices for Tissue Engineering and Regeneration".BIOMIMICKED BIOMATERIALS: ADVANCES IN TISSUE ENGINEERING AND REGENERATIVE MEDICINE 1250(2020):15-31. |
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