Melatonin lowers edema after spinal cord injury

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	Melatonin lowers edema after spinal cord injury
其他题名	Melatonin lowers edema after spinal cord injury
	Li Cheng 1; Chen Xiao 1; Qiaol Suchi 1; Liu Xinwei 2; Liu Chang 1; Zhu Degang 1; Su Jiacan 1; Wang Zhiwei 1
	2014
发表期刊	NEURAL REGENERATION RESEARCH
ISSN	1673-5374
卷号	9 期号:24 页码:2205-2210
摘要	Melatonin has been shown to diminish edema in rats. Melatonin can be used to treat spinal cord injury. This study presumed that melatonin could relieve spinal cord edema and examined how it might act. Our experiments found that melatonin (100 mg/kg, i.p.) could reduce the water content of the spinal cord, and suppress the expression of aquaporin-4 and glial fibrillary acidic protein after spinal cord injury. This suggests that the mechanism by which melatonin alleviates the damage to the spinal cord by edema might be related to the expression of aquaporin-4 and glial fibrillary acidic protein.
其他摘要	Melatonin has been shown to diminish edema in rats. Melatonin can be used to treat spinal cord injury. This study presumed that melatonin could relieve spinal cord edema and examined how it might act. Our experiments found that melatonin (100 mg
关键词	RANDOMIZED CONTROLLED-TRIAL AQUAPORIN-4 EXPRESSION TIRILAZAD MESYLATE SECONDARY INJURY ISCHEMIC-INJURY NEURONAL DEATH WATER CHANNELS BRAIN EDEMA METHYLPREDNISOLONE RATS nerve regeneration spinal cord injury melatonin edema aquaporin glial fibrillary acidic protein immunohistochemistry western blot assay neural regeneration
收录类别	CSCD
语种	英语
资助项目	[China Postdoctoral Science Foundation Grant]
CSCD记录号	CSCD:5325093
引用统计	被引频次：3[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/142273
专题	中国科学院金属研究所
作者单位	1.Second Mil Med University, Changhai Hosp, Dept Orthoped Surg, Shanghai 200433, Peoples R China 2.中国科学院金属研究所
推荐引用方式 GB/T 7714	Li Cheng,Chen Xiao,Qiaol Suchi,et al. Melatonin lowers edema after spinal cord injury[J]. NEURAL REGENERATION RESEARCH,2014,9(24):2205-2210.
APA	Li Cheng.,Chen Xiao.,Qiaol Suchi.,Liu Xinwei.,Liu Chang.,...&Wang Zhiwei.(2014).Melatonin lowers edema after spinal cord injury.NEURAL REGENERATION RESEARCH,9(24),2205-2210.
MLA	Li Cheng,et al."Melatonin lowers edema after spinal cord injury".NEURAL REGENERATION RESEARCH 9.24(2014):2205-2210.