| Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors | |
| Alternative Title | Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors |
| Liu Yan1; Zhong Wu1; Li Song1 | |
| 2012 | |
| Source Publication | CHINESE CHEMICAL LETTERS
 |
| ISSN | 1001-8417 |
| Volume | 23Issue:2Pages:133-136 |
| Abstract | A short and efficient synthesis of (Z)-2-substituted-5-(4-((2-substitued-5-oxoimidazolidin-4-ylidene)methyl)benzamido)benzoic acid derivatives (8a-g) as potential type of FabH inhibitors is described. Their structures were confirmed by MS, NOE and H-1 NMR. (C) 2011 Wu Zhong. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved. |
| Other Abstract | A short and efficient synthesis of(Z)-2-substituted-5-(4-((2-substitued-5-oxoimidazolidin-4-ylidene)methyl)benzamido)ben-zoic acid derivatives(8a-g) as potential type of FabH inhibitors is described.Their structures were confirmed by MS,NOE and ~1H NMR. |
| Keyword | FATTY-ACID SYNTHASE TUBERCULOSIS CLONING Tuberculosis Mycobacterium tuberculosis FabH Enzyme inhibitor Synthesis NOE |
| Indexed By | CSCD |
| Language | 英语 |
| Funding Project | [National High Technology Research and Development Program of China] |
| CSCD ID | CSCD:4448329 |
| Citation statistics |
Cited Times:1[CSCD]
[CSCD Record]
|
| Document Type | 期刊论文 |
| Identifier | http://ir.imr.ac.cn/handle/321006/142379 |
| Collection | 中国科学院金属研究所 |
| Affiliation | 1.Beijing Institute Pharmacol & Toxicol, Lab Comp Aided Drug Design & Discovery, Beijing 100850, Peoples R China 2.中国科学院金属研究所 |
| Recommended Citation GB/T 7714 | Liu Yan,Zhong Wu,Li Song. Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors[J]. CHINESE CHEMICAL LETTERS,2012,23(2):133-136. |
| APA | Liu Yan,Zhong Wu,&Li Song.(2012).Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors.CHINESE CHEMICAL LETTERS,23(2),133-136. |
| MLA | Liu Yan,et al."Syntheses and studies of hydantoin derivatives as potential anti-tuberculosis inhibitors".CHINESE CHEMICAL LETTERS 23.2(2012):133-136. |
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment