A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy

IMR OpenIR

	A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy
其他题名	A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy
	Hua Wei 1; Wang Dongmei 1; Cai Lin 1; Sun Chaofeng 1; Fu Guosheng 1; Wang Yutang 1; Yan Ji 1; Luo Zhiling 1; Xu Jing 1; Wang Zhiyong 1; Xu Geng 1; Shen Farong 1; Xu Wei 1; Wang Jingfeng 1; Ren Xuejun 1; Jin Wei 1; Zhang Nan 1; Lau Elizabeth OiYan 1; Zhang Shu 1
	2012
发表期刊	CHINESE MEDICAL JOURNAL
ISSN	0366-6999
卷号	125 期号:3 页码:428-433
摘要	Background Cardiac resynchronization therapy (CRT) with biventricular pacing improves cardiac function, functional capacity and quality of life in selected patients with heart failure. The current study aimed to evaluate the efficacy of the intracardiac electrogram (IEGM)-based optimization method, QuickOpt (TM), in Chinese patients treated with CRT.
其他摘要	Background Cardiac resynchronization therapy (CRT) with biventricular pacing improves cardiac function, functional capacity and quality of life in selected patients with heart failure. The current study aimed to evaluate the efficacy of the intracardiac electrogram (IEGM)-based optimization method, QuickOpt~(TM), in Chinese patients treated with CRT. Methods Aortic time velocity integrals (AVTI) achieved at the sensed atrioventricular (AV), paced AV and interventricular (VV) interval settings recommended by both QuickOpt~(TM) and standard echocardiographic optimization were measured in 101 patients. Consistency and the strength of the relationship between the two timing cycle optimization methods were assessed by intra-class correlation coefficient (ICC). Results The ICC showed good agreement and correlation with what the AVTI achieved at the optimal sensed AV (ICC=0.9683 (0.9535–0.9785)), paced AV (ICC=0.9642 (0.9475–0.9757)) and VV (ICC=0.9730 (0.9602–0.9817)) interval settings determined by the two optimization methods. The average time required by echocardiographic optimization and by QuickOpt~(TM) were (78.32±32.40) minutes and (1.98±1.64) minutes respectively (P <0.0001). Conclusion The QuickOpt~(TM) algorithm provides a quicker, simpler and reliable alternative to the standard method for timing cycle optimization. (ClinicalTrial.gov Reference Number: NCT00918294)
关键词	SEVERE HEART-FAILURE DELAY OPTIMIZATION CONDUCTION DELAY VV-DELAY ECHO ECHOCARDIOGRAPHY TRIAL heart failure cardiac resynchronization therapy atrioventricular interval interventricular interval timing cycle optimization echocardiography aortic velocity time integral intracardiac electrogram QuickOpt (TM)
收录类别	CSCD
语种	英语
资助项目	[St. Jude Medical Inc.] ; [China Health & Medical Development Foundation]
CSCD记录号	CSCD:4432881
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/142932
专题	中国科学院金属研究所
作者单位	1.Peking Union Med Coll 2.Chinese Acad Med Sci Dept Cardiol Cardiovasc Institute 3.中国医学科学院 4.中国科学院金属研究所 5.Chongqing Med University 6.Xi An Jiao Tong University 7.浙江大学 8.中国人民解放军总医院 9.Anhui Prov Hosp 10.Kunming Med Coll 11.Tianjin Chest Hosp 12.Inner Mongolian Peoples Hosp 13.Zhejiang Hosp 14.南京大学 15.Sun Yat Sen University 16.Capital Med University 17.上海交通大学
推荐引用方式 GB/T 7714	Hua Wei,Wang Dongmei,Cai Lin,et al. A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy[J]. CHINESE MEDICAL JOURNAL,2012,125(3):428-433.
APA	Hua Wei.,Wang Dongmei.,Cai Lin.,Sun Chaofeng.,Fu Guosheng.,...&Zhang Shu.(2012).A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy.CHINESE MEDICAL JOURNAL,125(3),428-433.
MLA	Hua Wei,et al."A prospective study to evaluate the efficacy of an intracardiac electrogram-based atrioventricular and interventricular intervals optimization method in cardiac resynchronization therapy".CHINESE MEDICAL JOURNAL 125.3(2012):428-433.