Alternative TitleThe application of micro-computed tomography (microCT) for the assessment of the effect of the new Iow elastic modulus β Ti alloy on bone healing of osteoporotic fracture in an animal model
沙漠; 郭征; 付军; 李述军; 李靖; 张涌泉; 吴智刚; 袁超凡; 石磊; 王军
Source Publication中国骨质疏松杂志
Other AbstractObjective To investigate the influence of the low-modulus of elasticity (30 GPa) fixation on bone healing of osteoporotie fracture and the effects of stress shielding by miero-CT. Methods Thirty female Sprague- Dawley rats, aged 3 months, were selected, OVX was performed twelve weeks before femur fracture, the fracture of left femur was stabilized with the high-modulus of elasticity titanium alloy pin and the right with the low-modulus of elasticity. The bony calluses were observed miero-CT at two, four, six, and twelve weeks after fracture. The parameters included BV, TV, BVF, Tb. Th, Tb. N, Tb. Sp, SMI. Results The calluses at the low-modulus of elasticity group showed a significantly lower percentage of mineralized bone at 2 - 4 weeks postoperatively, and a higher amount of fibrous callus than the high-modulus of elasticity group. The calluses were no longer distinguishable at 6 - 9 weeks. The superior trabecular bone mierostructure was produced and less bone loss were shown under the low-modulus of elasticity pin at 12 weeks. Conclusion The new low elastic modulus β Ti alloy seemed to increase the fibrous callus formation at the initial phase, and improve the quality of bone healing at the later phase.
Keyword弹性模量 钛合金 micro—CT 骨质疏松性骨折
Indexed ByCSCD
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Document Type期刊论文
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GB/T 7714
沙漠,郭征,付军,等. Micro—CT评价新型低弹β钛合金对动物骨质疏松性骨折愈合的影响[J]. 中国骨质疏松杂志,2007,13.0(010):704-708.
APA 沙漠.,郭征.,付军.,李述军.,李靖.,...&王军.(2007).Micro—CT评价新型低弹β钛合金对动物骨质疏松性骨折愈合的影响.中国骨质疏松杂志,13.0(010),704-708.
MLA 沙漠,et al."Micro—CT评价新型低弹β钛合金对动物骨质疏松性骨折愈合的影响".中国骨质疏松杂志 13.0.010(2007):704-708.
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