Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA

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	Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA
其他题名	Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA
	Pan LeiTing 1; Sun WenWu 2; Qi JiWei 1; Wu Xian 1; Song Kun 1; Hu Fen 1; Zhang XinZheng 1; Xu JingJun 1
	2009
发表期刊	PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
ISSN	1000-3282
卷号	36 期号:1 页码:83-87
摘要	Rat synoviocytes were cultured in vitro and the changing of cellular cytoskeleton induced by PMA was investigated with atomic force microscopy. PMA is usually used to stimulate PKC signal transduction pathway in synoviocytes and to simulate process of inflammation. The results presented here show that synoviocyte cytoskeleton has changed significantly after PKC activation by using the imaging of atomic force microscopy. The results also indicate that the activation of PKC might play crucial role in cytoskeleton changing of synoviocytes, which, to some extent, provides some experiments and ideas on understanding the mechanism underlying rheumatoid arthritis (RA).
关键词	ATOMIC-FORCE MICROSCOPY PROTEIN-KINASE-C RHEUMATOID-ARTHRITIS CORTICAL CYTOSKELETON SYNOVIAL FIBROBLASTS ACTIN CYTOSKELETON CELLS ACTIVATION synoviocytes cytoskeleton PMA PKC atomic force microscopy
收录类别	CSCD
语种	英语
资助项目	[National Basic Research Program of China] ; [Key International S&T Cooperation Project of China] ; [Programme of Introducing Talents of Displine to Universities]
CSCD记录号	CSCD:3487928
引用统计
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/144178
专题	中国科学院金属研究所
作者单位	1.南开大学 2.中国科学院金属研究所
推荐引用方式 GB/T 7714	Pan LeiTing,Sun WenWu,Qi JiWei,et al. Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA[J]. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,2009,36(1):83-87.
APA	Pan LeiTing.,Sun WenWu.,Qi JiWei.,Wu Xian.,Song Kun.,...&Xu JingJun.(2009).Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA.PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS,36(1),83-87.
MLA	Pan LeiTing,et al."Study of Cytoskeleton Change in Rat Synoviocytes Induced by PMA".PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS 36.1(2009):83-87.