Risk factors of precancerous gastric lesions in a population at high risk of gastric cancer

IMR OpenIR

	Risk factors of precancerous gastric lesions in a population at high risk of gastric cancer
其他题名	Risk Factors of Precancerous Gastric Lesions in A Population at High Risk of Gastric Cancer
	Liu Jian; Sun LiPing; Gong YueHua; Yuan Yuan
	2010
发表期刊	CHINESE JOURNAL OF CANCER RESEARCH
ISSN	1000-9604
卷号	22 期号:4 页码:267-273
摘要	In cancer prevention, the targeting of precancerous lesions has been recognized as the most promising method. However, little attention has been paid to the risk factors of precancerous gastric lesions, especially in rural China where there is high prevalence of precancerous gastric lesions. We therefore conducted a cross-sectional study in Liaoning province, China, to investigate the potential risk and protective factors of these precancerous gastric lesions.
其他摘要	Objective:In cancer prevention,the targeting of precancerous lesions has been recognized as the most promising method.However,little attention has been paid to the risk factors of precancerous gastric lesions,especially in rural China where there is high prevalence of precancerous gastric lesions.We therefore conducted a cross-sectional study in Liaoning province,China,to investigate the potential risk and protective factors of these precancerous gastric lesions. Methods:A total of 1,179 subjects with high risk of gastric cancer from Zhuanghe County were included in this study.Standard questionnaires were used in collecting epidemiological factors and the data were then analyzed by the unconditional logistic regression model. Results:Smoking and drinking were the risk factors for the precancerous gastric lesions among rural subjects,and the association of smoking or drinking and the precancerous gastric lesions increased in strength with the daily consumption and duration.As the factors such as age,gender,smoking,alcohol were controlled,a multivariable analysis revealed that there was a significant correlation between the deep-fry food intake and the gastric epithelial dysplasia with the odds ratio(OR)of 1.7895%confidence interval(CI):1.01-3.12.Garlic eating was shown to confer protection against the development of gastric ulcer(OR=0.55,95%CI:0.33-0.92). Conclusion:Smoking and drinking were the risk factors for the precancerous gastric lesions among rural subjects. Deep-fry food intake might be one of the risk factors for the precancerous gastric lesions and garlic eating was shown to confer protection against the development of gastric ulcer among rural Chinese population
关键词	HELICOBACTER-PYLORI INFECTION ATROPHIC GASTRITIS CIGARETTE-SMOKING DISEASE PREVALENCE EXPRESSION VENEZUELA STOMACH HABITS TRIAL Risk factors Precancerous gastric lesions High risk of gastric cancer
收录类别	CSCD
语种	英语
资助项目	[National Tenth Five-year Study Program for Taking Key Scientific Problems of China] ; [Science Program of Liaoning Province]
CSCD记录号	CSCD:4075596
引用统计	被引频次：3[CSCD] [CSCD记录]
文献类型	期刊论文
条目标识符	http://ir.imr.ac.cn/handle/321006/145003
专题	中国科学院金属研究所
作者单位	中国科学院金属研究所
推荐引用方式 GB/T 7714	Liu Jian,Sun LiPing,Gong YueHua,et al. Risk factors of precancerous gastric lesions in a population at high risk of gastric cancer[J]. CHINESE JOURNAL OF CANCER RESEARCH,2010,22(4):267-273.
APA	Liu Jian,Sun LiPing,Gong YueHua,&Yuan Yuan.(2010).Risk factors of precancerous gastric lesions in a population at high risk of gastric cancer.CHINESE JOURNAL OF CANCER RESEARCH,22(4),267-273.
MLA	Liu Jian,et al."Risk factors of precancerous gastric lesions in a population at high risk of gastric cancer".CHINESE JOURNAL OF CANCER RESEARCH 22.4(2010):267-273.