Alternative TitleSingle cell gel electrophoresis of a magnesium alloy coated with β-tricalcium phosphate
郝玉全1; 谭丽丽2; 颜廷亭2; 阎秀林1; 杨柯2; 艾红军1
Source Publication中华口腔医学杂志
Other AbstractObjective To evaluate the genotoxicity of a magnesium alloy coated with β-tricalcium phosphate(β-TCP). Methods Four groups were designed. In the first group, AZ31B magnesium alloy surface was coated with β-TCP using chemical bath deposition, and in the second group magnesium alloy was tested. The other two groups were negative control (pure titanium ) and positive control groups (0.5mg/L bleomycin). Single cell gel electrophoresis was adopted to investigate genotoxicity of the alloy samples in different groups, and 60 cells from each group were analysed. Tail moment and tail DNA percentage were used as reliable indicators to show DNA damage in lymphocytes induced by every testing sample. Student- Newman-Keuls(SNK) test was used to compare results from 4 groups. Results There were no significant differences in tail moment and tail DNA percentage between magnesium alloy group (0.52±0.12), (6.82±1.81)% and magnesium alloy coated with β-TCP group(0.51±0.12), (6.89±1.93)% ,P 〉0.05. Tail moment and tail DNA percentage in negative group were (0.47±0.14) and (6.29±1.64)%, and tail moment and tail DNA percentage in positive group were (5.17±1.23) and (22.09±4.51)%. Conclusions No significant increase was found in DNA damage in lymphocytes induced by magnesium alloy coated with β-TCP.
Keyword 磷酸钙类 彗星试验
Indexed ByCSCD
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Document Type期刊论文
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GB/T 7714
郝玉全,谭丽丽,颜廷亭,等. 镁合金表面沉积β-磷酸三钙涂层的单细胞凝胶电泳实验[J]. 中华口腔医学杂志,2009,44.0(010):626-628.
APA 郝玉全,谭丽丽,颜廷亭,阎秀林,杨柯,&艾红军.(2009).镁合金表面沉积β-磷酸三钙涂层的单细胞凝胶电泳实验.中华口腔医学杂志,44.0(010),626-628.
MLA 郝玉全,et al."镁合金表面沉积β-磷酸三钙涂层的单细胞凝胶电泳实验".中华口腔医学杂志 44.0.010(2009):626-628.
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